Publications
Multi-omics in Aging: Mapping Host-Microbiome Metabolic Networks for Anti-Aging Insights
- 2025
- Shotgun Metagenomics
- Mouse
FBP1 Controls Liver Cancer Evolution from Senescent MASH Hepatocytes
- 2025
- Plant and Animal Sequencing
- Animal
Liver-innervating vagal sensory neurons are indispensable for the development of hepatic steatosis and anxiety-like behavior in diet-induced obese mice
- 2025
- Spatial Transcriptome Sequencing
- Animal
Histone H1 deamidation facilitates chromatin relaxation for DNA repair
- 2025
- ATAC-seq
- Human
Case Study
Novogene 10x Single Cell RNA Sequencing: Project Experience Showcase - Mouse Spleen Tissue
- 2025
- 10X Genomics single cell sequencing
- Animal
- Case Study
Case Study_10x Spatial-Spatial Isoforms Reveal the Mechanisms of Metastasis
- 2025
- Spatial Transcriptome Sequencing
- Animal
- Case Study
Lab Case Study_Spatial project experience showcase
- 2025
- Spatial Transcriptome Sequencing
- Animal
- Case Study
High-quality genome of a modern soybean cultivar and resequencing of 547 accessions provide insights into the role of structural variation
- 2025
- Plant and Animal Sequencing
- Plant
- Case Study
Introduction of Untargeted Metabolomics
- 2025
- Metabolomics, Untargted Metabolomics
- Mouse
- Case Study
Histone H1 deamidation facilitates chromatin relaxation for DNA repair
- 2025
- ATAC-seq
- Human
- Case Study
Liver-innervating vagal sensory neurons are indispensable for the development of hepatic steatosis and anxiety-like behavior in diet-induced obese mice
- 2025
- Spatial Transcriptome Sequencing
- Animal
- Case Study
FBP1 Controls Liver Cancer Evolution from Senescent MASH Hepatocytes
- 2025
- Plant and Animal Sequencing
- Animal
- Case Study
Multi-omics in Aging: Mapping Host-Microbiome Metabolic Networks for Anti-Aging Insights
- 2025
- Shotgun Metagenomics
- Mouse
- Case Study
Novogene Single-cell and Spatial Multi-omics Case Study
- 2024
- Single Cell RNA Sequencing
- Human
- Case Study
Setaria Pan-Genome Variation: Unraveling the Story of Domestication
- 2024
- Plant
- Case Study
Novogene Single-cell and Spatial Multi-omics Case Study Ⅱ
- 2024
- 10X Genomics single cell sequencing
- Human
- Case Study
Novogene 10x Single Cell RNA Sequencing: Project Experience Showcase
- 2024
- 10X Genomics single cell RNA sequencing
- Animal
- Case Study
Telomere-to-telomere Pear (Pyrus pyrifolia) Reference Genome Reveals Duplication-Driven Genome Evolution
- 2024
- Long-read sequencing
- Plant
- Case Study
Novogene 10x Single Cell RNA Sequencing: Project Experience Showcase Series 2
- 2024
- 10X Genomics single cell sequencing
- Animal
- Case Study
Novogene Single-cell and Spatial Multi-omics Case Study Ⅲ
- 2024
- 10X Genomics single cell sequencing
- Human
- Case Study
Single-Cell RNA-Seq of the Developing Cardiac Outflow Tract Reveals Convergent Development of the Vascular Smooth Muscle Cells
- 2024
- 10X Genomics single cell RNA sequencing
- Mouse
- Case Study
Stress-Induced Metabolic Disorder in Peripheral CD4+ T Cells Leads to Anxiety-like Behavior
- 2024
- 10X Genomics single cell RNA sequencing
- Mouse
- Case Study
Therapy-induced APOBEC3A Drives Evolution of Persistent Cancer Cells
- 2024
- Whole Genome Sequencing
- Human
- Case Study
Novogene 10x Single Cell RNA Sequencing: Project Experience Showcase Series 3
- 2024
- 10X Genomics single cell sequencing
- Animal
- Case Study
Molecular Evolution and Increasing Macrolide Resistance of Bordetella pertussis
- 2024
- Whole Genome Sequencing
- Human
- Case Study
Novogene Single-cell and Spatial Multi-omics Case Study IV
- 2024
- 10X Genomics single cell sequencing
- Human
- Case Study
360° Q&A Series: Quick Tips to Help You Select the Most Suitable RNA Sequencing
- 2024
- RNA Sequencing
- Human
360° Q&A Series: Quick Guide to Utilize RNA Sequencing
- 2024
- RNA Sequencing
- Human
The Application of Multiomics in the Gut-brain Axis of Honeybee Model
- 2023
- Animal
- Case Study
Novogene's Single-Cell Sequencing Services Facilitate Mammalian Stem Cell Regeneration Research
- 2023
- 10X Genomics single cell sequencing
- Animal
- Customer Interview
The Application of RNA Sequencing in Systemic Lupus Erythematosus
- 2023
- RNA Sequencing
- Animal
- Case Study
Application of Whole Transcriptome Sequencing in Cancer Research
- 2023
- Whole Transcriptome Sequencing
- Human
- Case Study
Transgenerational inheritance of acquired epigenetic signatures at CpG islands in mice
- 2023
- Whole Genome Sequencing, Whole Genome Bisulfite Sequencing (WGBS)
- Animal
- CELL
- IF 66.85
Pangenomic analysis identifies structural variation associated with heat tolerance in pearl millet
- 2023
- De novo Sequencing, Whole Genome Sequencing, Hi-C
- Plant
- NATURE GENETICS
- IF 41.307
IGF2BP1 induces neuroblastoma via a druggable feedforward loop with MYCN promoting 17q oncogene expression
- 2023
- RNA Sequencing, Whole Genome Sequencing
- Human
- Molecular Cancer
- IF 41.444
Neurulation of the cynomolgus monkey embryo achieved from 3D blastocyst culture
- 2023
- RNA Sequencing, Whole Genome Sequencing
- Animal
- CELL
- IF 66.85
An unusual tandem kinase fusion protein confers leaf rust resistance in wheat
- 2023
- RNA Sequencing, Whole Genome Sequencing
- Plant
- NATURE GENETICS
- IF 41.307
Therapy-induced APOBEC3A drives evolution of persistent cancer cells
- 2023
- Whole Genome Sequencing
- Human
- NATURE
- IF 64.8
A graph-based genome and pan-genome variation of the model plant Setaria
- 2023
- Whole Genome Sequencing
- Plant
- NATURE GENETICS
- IF 30.8
Historical DNA reveals climate adaptation in an endangered songbird
- 2023
- Whole Genome Sequencing
- Animal
- Nature Climate Change
- IF 30.7
Rapid Discovery of Functional NLRs Using the Signature of High Expression, High-Throughput Transformation, and Large-Scale Phenotyping
- 2023
- Whole Genome Sequencing
- Animal
- CELL
- IF 66.85
The evolution of white-tailed jackrabbit camouflage in response to past and future seasonal climates
- 2023
- Whole Genome Sequencing
- Animal
- SCIENCE
- IF 63.714
Precise integration of large DNA sequences in plant genomes using PrimeRoot editors
- 2023
- Whole Genome Sequencing
- Plant
- NATURE BIOTECHNOLOGY
- IF 68.164
Improved cytosine base editors generated from TadA variants
- 2023
- Whole Genome Sequencing
- Human
- NATURE BIOTECHNOLOGY
- IF 46.9
Resurrection of endogenous retroviruses during aging reinforces senescence
- 2023
- RNA Sequencing, Whole Genome Bisulfite Sequencing (WGBS)
- Microbial
- CELL
- IF 66.85
Y chromosome loss in cancer drives growth by evasion of adaptive immunity
- 2023
- RNA Sequencing, Whole Exome Sequencing
- Human
- NATURE
- IF 64.8
An integrated cellular and molecular model of gastric neuroendocrine cancer evolution highlights therapeutic targets
- 2023
- Whole Exome Sequencing
- Human
- CANCER CELL
- IF 50.3
Camrelizumab Plus Apatinib in Patients With Recurrent or Metastatic Nasopharyngeal Carcinoma: An Open-Label, Single-Arm, Phase II Study
- 2023
- Whole Exome Sequencing
- Human
- JOURNAL OF CLINICAL ONCOLOGY
- IF 50.717
Comprehensive molecular phenotyping of ARID1A-deficient gastric cancer reveals pervasive epigenomic reprogramming and therapeutic opportunities
- 2023
- Whole Exome Sequencing
- Human
- GUT
- IF 31.793
RPS15 interacted with IGF2BP1 to promote esophageal squamous cell carcinoma development via recognizing m6A modification
- 2023
- Ribo-seq
- Human
- Signal Transduction and Targeted Therapy
- IF 39.3
Salmonella-liberated dietary L-arabinose promotes expansion in superspreaders.
- 2023
- RNA Sequencing
- Microbial
- Cell Host & Microbe
- IF 31.316
Metavirome of 31 tick species provides a compendium of 1,801 RNA virus genomes
- 2023
- Metatranscriptome Sequencing
- Animal
- Nature Microbiology
- IF 30.964
Developmentally programmed early-age skin localization of iNKT cells supports local tissue development and homeostasis
- 2023
- Metagenomics, RNA Sequencing
- Human
- NATURE IMMUNOLOGY
- IF 30.5
Differential Responses of the Gut Microbiome and Resistome to Antibiotic Exposures in Infants and Adults
- 2023
- 16S/18S/ITS Amplicon Metagenomic Sequencing, Metagenomics
- Microbial
- Cell Host & Microbe
- IF 31.316
Hyperactive nanobacteria with host-dependent traits pervade Omnitrophota
- 2023
- Metagenomics
- Microbial
- Nature Microbiology
- IF 30.964
Linking chromatin acylation mark-defined proteome and genome in living cells
- 2023
- ATAC-seq, ChIP-seq, RNA Sequencing, Hi-C
- Human
- CELL
- IF 66.85
Nano-DMS-MaP allows isoform-specific RNA structure determination
- 2023
- RNA Sequencing, Whole Genome Sequencing
- Human
- NATURE METHODS
- IF 47.99
ThPOK is a critical multifaceted regulator of myeloid lineage development
- 2023
- RNA Sequencing
- Human
- NATURE IMMUNOLOGY
- IF 30.5
cGLRs are a diverse family of pattern recognition receptors in innate immunity
- 2023
- RNA Sequencing
- Human
- CELL
- IF 64.5
Upf3a but not Upf1 mediates the genetic compensation response induced by leg1 deleterious mutations in an H3K4me3-independent manner
- 2023
- RNA Sequencing
- Animal
- Cell Discovery
- IF 33.5
Anti-GD2 CAR-NKT cells in relapsed or refractory neuroblastoma: updated phase 1 trial interim results
- 2023
- RNA Sequencing
- Human
- NATURE MEDICINE
- IF 87.241
Mitotic clustering of pulverized chromosomes from micronuclei
- 2023
- RNA Sequencing
- Human
- NATURE
- IF 69.504
Antagonizing the irreversible thrombomodulin-initiated proteolytic signaling alleviates age-related liver fibrosis via senescent cell killing
- 2023
- RNA Sequencing
- Human
- CELL RESEARCH
- IF 46.297
The wheat stem rust resistance gene Sr43 encodes an unusual protein kinase
- 2023
- RNA Sequencing
- Plant
- NATURE GENETICS
- IF 41.307
3-Hydroxybutyrate ameliorates insulin resistance by inhibiting PPARγ Ser273 phosphorylation in type 2 diabetic mice
- 2023
- RNA Sequencing
- Human
- Signal Transduction and Targeted Therapy
- IF 38.104
PI3Kβ controls immune evasion in PTEN-deficient breast tumours
- 2023
- RNA Sequencing
- Human
- NATURE
- IF 69.504
Super-enhancer-driven TOX2 mediates oncogenesis in Natural Killer/T Cell Lymphoma
- 2023
- RNA Sequencing
- Human
- Molecular Cancer
- IF 41.444
Climate change and vector-borne diseases: a multi-omics approach of temperature-induced changes in the mosquito
- 2023
- RNA Sequencing
- Animal
- JOURNAL OF TRAVEL MEDICINE
- IF 39.194
Overcoming resistance to immunotherapy by targeting GPR84 in myeloid-derived suppressor cells
- 2023
- RNA Sequencing
- Human
- Signal Transduction and Targeted Therapy
- IF 38.104
RBM4 dictates ESCC cell fate switch from cellular senescence to glutamine-addiction survival through inhibiting LKB1-AMPK-axis
- 2023
- RNA Sequencing
- Human
- Signal Transduction and Targeted Therapy
- IF 38.104
Microfluidic templated stem cell spheroids microneedles for diabetic wound treatment
- 2023
- RNA Sequencing
- Human
- ADVANCED MATERIALS
- IF 32.086
Liberation of daidzein by gut microbial β-galactosidase suppresses acetaminophen-induced hepatotoxicity in mice
- 2023
- RNA Sequencing
- Microbial
- Cell Host & Microbe
- IF 31.316
Fusobacterium nucleatum aggravates rheumatoid arthritis through FadA-containing outer membrane vesicles
- 2023
- RNA Sequencing
- Human
- Cell Host & Microbe
- IF 31.316
Macrophage fumarate hydratase restrains mtRNA-mediated interferon production
- 2023
- RNA Sequencing
- Human
- NATURE
- IF 69.504
Endoplasmic reticulum stress in the intestinal epithelium initiates purine metabolite synthesis and promotes Th17 cell differentiation in the gut
- 2023
- RNA Sequencing
- Microbial
- IMMUNITY
- IF 43.474
Tumor PD-L1 engages myeloid PD-1 to suppress type I interferon to impair cytotoxic T lymphocyte recruitment.
- 2023
- RNA Sequencing
- Human
- CANCER CELL
- IF 38.585
GOT1 constrains TH17 cell differentiation, while promoting iTreg cell differentiation
- 2023
- RNA Sequencing
- Human
- NATURE
- IF 69.504
PIKFYVE inhibition mitigates disease in models of diverse forms of ALS
- 2023
- RNA Sequencing
- Human
- CELL
- IF 66.85
IDH2 and TET2 mutations synergize to modulate T Follicular Helper cell functional interaction with the AITL microenvironment.
- 2023
- RNA Sequencing
- Human
- CANCER CELL
- IF 38.585
Discovery of Targets for Immune–Metabolic Antitumor Drugs Identifies Estrogen-Related Receptor Alpha
- 2023
- RNA Sequencing
- Human
- Cancer Discovery
- IF 38.272
Targeting PSAT1 to mitigate metastasis in tumors with p53-72Pro variant
- 2023
- RNA Sequencing
- Human
- Signal Transduction and Targeted Therapy
- IF 38.104
Precise transcript targeting by CRISPR-Csm complexes
- 2023
- RNA Sequencing
- Microbial
- NATURE BIOTECHNOLOGY
- IF 68.164
Discovery of IHMT-337 as a potent irreversible EZH2 inhibitor targeting CDK4 transcription for malignancies
- 2023
- RNA Sequencing
- Human
- Signal Transduction and Targeted Therapy
- IF 38.104
Diurnal transcriptome landscape of a multi-tissue response to time-restricted feeding in mammals
- 2023
- RNA Sequencing
- Animal
- Cell Metabolism
- IF 31.373
Human TH17 cells engage gasdermin E pores to release IL-1α on NLRP3 inflammasome activation
- 2023
- RNA Sequencing
- Human
- NATURE IMMUNOLOGY
- IF 31.25
Cancer cell employs a microenvironmental neural signal trans-activating nucleus-mitochondria coordination to acquire stemness
- 2023
- RNA Sequencing, CUT&Tag
- Human
- Signal Transduction and Targeted Therapy
- IF 39.3
Homology-independent targeted insertion (HITI) enables guided CAR knock-in and efficient clinical scale CAR-T cell manufacturing
- 2023
- CRISPR Screening (off-target)
- Human
- Molecular Cancer
- IF 37.3
The compact Casπ (Cas12l) ‘bracelet’ provides a unique structural platform for DNA manipulation
- 2023
- CRISPR Screening (off-target)
- Animal
- CELL RESEARCH
- IF 46.297
DNA hypomethylation silences anti-tumor immune genes in early prostate cancer and CTCs
- 2023
- ChIP-seq, RNA Sequencing, Whole Genome Bisulfite Sequencing (WGBS)
- Human
- CELL
- IF 64.5
Critically short telomeres derepress retrotransposons to promote genome instability in embryonic stem cells
- 2023
- ChIP-seq, RNA Sequencing, Whole Genome Bisulfite Sequencing (WGBS)
- Animal
- Cell Discovery
- IF 38.079
Rewiring cancer drivers to activate apoptosis
- 2023
- ChIP-seq, RNA Sequencing
- Human
- NATURE
- IF 64.8
(R)-2-hydroxyglutarate inhibits KDM5 histone lysine demethylases to drive transformation in IDH-mutant cancers
- 2023
- ChIP-seq, RNA Sequencing
- Human
- Cancer Discovery
- IF 38.272
Cycles of satellite and transposon evolution in Arabidopsis centromeres
- 2023
- ChIP-seq
- Plant
- NATURE
- IF 69.504
Ornithine aminotransferase supports polyamine synthesis in pancreatic cancer
- 2023
- ATAC-seq, RNA Sequencing
- Human
- NATURE
- IF 69.504
Cell Reprogramming-Inspired Dynamically Responsive Hydrogel Boosts the Induction of Pluripotency via Phase-Separated Biomolecular Condensates
- 2023
- ATAC-seq
- Human
- ADVANCED MATERIALS
- IF 32.086
Influenza-trained mucosal-resident alveolar macrophages confer long-term antitumor immunity in the lungs
- 2023
- ATAC-seq
- Microbial
- NATURE IMMUNOLOGY
- IF 31.25
Annelid functional genomics reveal the origins of bilaterian life cycles
- 2023
- ATAC-seq
- Animal
- NATURE
- IF 69.504
Cysteine carboxyethylation generates neoantigens to induce HLA-restricted autoimmunity
- 2023
- 10X Genomics single cell sequencing
- Animal
- SCIENCE
- IF 63.714
Lysine catabolism reprograms tumour immunity through histone crotonylation
- 2023
- 10X Genomics single cell sequencing, ChIP-seq, RNA Sequencing
- Human
- NATURE
- IF 69.504
Dietary tryptophan metabolite released by intratumoral Lactobacillus reuteri facilitates immune checkpoint inhibitor treatment
- 2023
- 10X Genomics single cell sequencing
- Human
- CELL
- IF 66.85
A differentiation roadmap of murine placentation at single-cell resolution
- 2023
- 10X Genomics single cell sequencing
- Animal
- Cell Discovery
- IF 38.079
NK-like CD8+ γδ T cells are expanded in persistent Mycobacterium tuberculosis infection
- 2023
- 10X Genomics single cell sequencing
- Human
- Science Immunology
- IF 30.63
Single-cell dissection of human hematopoietic reconstitution after allogeneic hematopoietic stem cell transplantation
- 2023
- 10X Genomics single cell sequencing
- Human
- Science Immunology
- IF 30.63
A TLR7-nanoparticle adjuvant promotes a broad immune response against heterologous strains of influenza and SARS-CoV-2
- 2023
- 10X Genomics single cell sequencing
- Microbial
- NATURE MATERIALS
- IF 47.656
Single-cell transcriptomic analysis of endometriosis
- 2023
- 10X Genomics single cell sequencing
- Human
- NATURE GENETICS
- IF 41.307
Drosophila Histone Demethylase KDM5 Regulates Social Behavior through Immune Control and Gut Microbiota Maintenance
- 2023
- 16S/18S/ITS Amplicon Metagenomic Sequencing, RNA Sequencing
- Microbial
- Case Study
A survey of the sorghum transcriptome using single-molecule long reads
- 2023
- Isoform Sequencing
- Plant
- Case Study
Targeted exome sequencing for the identification of common mutational signatures and potential driver mutations for brain metastases and prognosis summary
- 2023
- Target Region Sequencing
- Human
- Case Study
Bat Immunity: Unlocking the Lineage-Specific Molecular Adaptations with Genetic Bases
- 2023
- De novo Sequencing, Whole Exome Sequencing, Hi-C
- Animal
- Case Study
Pangenomic analysis identifies structural variation associated with heat tolerance in pearl millet
- 2023
- Whole Genome Sequencing
- Plant
- Case Study
On the accuracy of the epigenetic copy machine: comprehensive specificity analysis of the DNMT1 DNA methyltransferase
- 2023
- Nucleic Acids Research
- Animal
- 19.16
- Case Study
Synergetic effects of microbial-phytoremediation reshape microbial communities and improve degradation of petroleum contaminants
- 2022
- 16S/18S/ITS Amplicon Metagenomic Sequencing
- Microbial
- IF 10.58
Biosynthesis and recycling of magnetite nanocatalysts from Fe-rich sludge
- 2022
- 16S/18S/ITS Amplicon Metagenomic Sequencing
- Microbial
- IF 10.2
Unveiling E2F4, TEAD1 and AP-1 as regulatory transcription factors of the replicative senescence program by multi-omics analysis
- 2022
- Reduced Representation Bisulfite Sequencing (RRBS)
- Animal
- IF 14.87
Histone H3K27 Methylation Perturbs Transcriptional Robustness and Underpins Dispensability of Highly Conserved Genes in Fungi
- 2022
- Whole Genome Bisulfite Sequencing (WGBS)
- Microbial
- IF 16.24
Neuronal NR4A1 deficiency drives complement-coordinated synaptic stripping by microglia in a mouse model of lupus
- 2022
- Whole Transcriptome Sequencing
- Animal
- IF 18.187
Cullin 4b-RING ubiquitin ligase targets IRGM1 to regulate Wnt signaling and intestinal homeostasis
- 2022
- Whole Transcriptome Sequencing
- Animal
- IF 15.828
Metagenomics combined with comprehensive validation as a public health risk assessment tool for urban and agricultural run-off
- 2022
- Metagenomics
- Microbial
- IF 11.236
Liver cancer heterogeneity modeled by in situ genome editing of hepatocytes
- 2022
- Whole Exome Sequencing, Whole Transcriptome Sequencing
- Animal
- IF 14.957
The dynamics of hybridisation between an avian island endemic and a recent coloniser
- 2022
- Whole Genome Sequencing
- Animal
- Case Study
Applications of Single-cell sequencing in stem cells, cancer, and skin research
- 2022
- Single Cell RNA Sequencing
- Human
- Case Study
The first fungi: mode of delivery determines early life fungal colonization in the intestine of preterm infants
- 2022
- 16S/18S/ITS Amplicon Metagenomic Sequencing
- Human
- Case Study
A Fifteen-Gene Classifier to Predict Neoadjuvant Chemotherapy Responses in Patients with Stage IB to IIB Squamous Cervical Cancer
- 2021
- Whole Exome Sequencing
- Human
- Advanced Science
- IF15.84
Clonal architecture in mesothelioma is prognostic and shapes the tumour microenvironment
- 2021
- Whole Exome Sequencing
- Human
- Nature Communications
- IF 12.121
Constitutive GLI1 expression in chondrosarcoma is regulated by major vault protein via mTOR/S6K1 signaling cascade
- 2021
- RNA Sequencing
- Human
- Cell Death & Differentiation
- IF 10.717
A comprehensive epigenome atlas reveals DNA methylation regulating skeletal muscle development
- 2021
- ATAC-seq, ChIP-seq, Whole Genome Bisulfite Sequencing (WGBS)
- Animal
- Nucleic Acids Res
- IF 11.501
High-throughput screening in postimplantation haploid epiblast stem cells reveals Hs3st3b1 as a modulator for reprogramming
- 2021
- Whole Genome Sequencing
- Animal
- Stem Cells Translational Medicine
- IF 11.5
Large-scale translatome profiling annotates the functional genome and reveals the key role of genic 3′ untranslated regions in translatomic variation in plants
- 2021
- RNA Sequencing, Ribo-seq
- Plant
- Plant Communications
Homology-mediated inter-chromosomal interactions in hexaploid wheat lead to specific subgenome territories following polyploidization and introgression
- 2021
- RNA Sequencing, Whole Genome Sequencing, Whole Genome Bisulfite Sequencing (WGBS)
- Plant
- Genome Biology
- IF 10.806
The Genetic Landscape of Hepatocellular Carcinoma: The Role of One Oncogene.
- 2021
- Whole Exome Sequencing
- Human
- Case Study
A modern Egyptian: the first comprehensive Egyptian reference genome
- 2021
- De novo Sequencing
- Human
The Gut Microbiome and Energy Source of the Giant Panda
- 2021
- Metagenomics
- Human
- Case Study
SMRT sequencing yields the chromosome-scale reference genome of tea tree, Camellia sinensis var. sinensis
- 2020
- De novo Sequencing
- Plant
- BioRxiv
The genome of jojoba (Simmondsia chinensis): A taxonomically isolated species that directs wax ester accumulation in its seeds
- 2020
- De novo Sequencing
- Plant
- Science Advances
- IF 12.804
SMRT sequencing generates the chromosome-scale reference genome of tropical fruit mango Mangifera indica
- 2020
- De novo Sequencing
- Plant
- BioRxiv
Horizontal gene transfer of Fhb7 for Fusarium head blight resistance in wheat
- 2020
- De novo Sequencing, RNA Sequencing
- Plant
- Science
- Case Study
A Genomic and Epigenomic Atlas of Prostate Cancer in Asian Populations
- 2020
- RNA Sequencing, Whole Genome Bisulfite Sequencing (WGBS)
- Human
- Nature Genetics
Resistance Gene Cloning from a Wild Crop Relative by Sequence Capture and Association Genetics
- 2020
- Target Region Sequencing
- Plant
- Nature Biotechnology
Integrated analysis of microbiome and host transcriptome reveals correlations between gut microbiota and clinical outcomes in HBV-related hepatocellular carcinoma
- 2020
- 16S/18S/ITS Amplicon Metagenomic Sequencing
- Human
- Genome Medicine
- IF 10.675
Relief of Biofilm Hypoxia Using an Oxygen Nanocarrier: A New Paradigm for Enhanced Antibiotic Therapy
- 2020
- Whole Genome Sequencing
- Microbial
- Advanced science
- IF 15.84
Stress-Induced Metabolic Disorder in Peripheral CD4+ T Cells Leads to Anxiety-like Behavio
- 2019
- 10X Genomics single cell sequencing
- Animal
- Cell
- 31.398
B1 oligomerization regulates PML nuclear body biogenesis and leukemogenesis
- 2019
- 10X Genomics single cell sequencing
- Animal
- Nature Communications
- 11.878
Pathogen-targeting glycovesicles as a therapy for salmonellosis
- 2019
- 16S/18S/ITS Amplicon Metagenomic Sequencing
- Microbial
- Nature Communications
- 11.878
Sexual Dimorphism of Gut Microbiota Dictates Therapeutics Efficacy of Radiation Injuries
- 2019
- 16S/18S/ITS Amplicon Metagenomic Sequencing
- Microbial
- Advanced Science
- 15.804
Drosophila Histone Demethylase KDM5 Regulates Social Behavior through Immune Control and Gut Microbiota Maintenance
- 2019
- 16S/18S/ITS Amplicon Metagenomic Sequencing
- Microbial
- Cell Host & Microbe
- 17.87
Hematopoietic PBX-interacting protein mediates cartilage degeneration during the pathogenesis of osteoarthritis.
- 2019
- ChIP-seq
- Human
- nature communications
- 12.353
A circRNA signature predicts postoperative recurrence in stage II/III colon cancer
- 2019
- circular RNA Sequencing
- Human
- EMBO Mol Med
- 10.624
The chromosome-scale reference genome of black pepper provides insight into piperine biosynthesis
- 2019
- De novo Sequencing
- Plant
- Nature communications
- 12.353
The chromosome-scale reference genome of black pepper provides insight into piperine biosynthesis
- 2019
- De novo Sequencing
- Plant
- Nature communications
- 12.353
Penaeid shrimp genome provides insights into benthic adaptation and frequent molting
- 2019
- De novo Sequencing
- Animal
- Nature communications
- 12.353
Stress-induced metabolic disorder in peripheral CD4+ T cells leads to anxiety-like behavior
- 2019
- Metabonomics
- Animal
- Cell
- 36.216
Marine biofilms constitute a bank of hidden microbial diversity and functional potential
- 2019
- Metagenomics
- Microbial
- Nature Communications
- 11.878
Mobile antibiotic resistome in wastewater treatment plants revealed by Nanopore metagenomic sequencing
- 2019
- Metagenomics
- Microbial
- Microbiome
- 10.465
Architecture of African Swine Fever Virus and implications for viral assembly
- 2019
- Proteomics
- Microbial
- Science
- 41.037
KIBRA controls exosome secretion via inhibiting the proteasomal degradation of Rab27a
- 2019
- Proteomics
- Animal
- Nature Communications
- 12.353
RNA methylomes reveal the m6A-mediated regulation of DNA demethylase gene SlDML2 in tomato fruit ripening
- 2019
- meRIP-seq
- Plant
- Genome Biology
- 14.028
Integrated multiomic analysis reveals comprehensive tumour heterogeneity and novel immunophenotypic classification in hepatocellular carcinomas
- 2019
- RNA Sequencing
- Human
- Acta Pharmaceutica Sinica B
- 17.943
Fine-Tuning of PGC1α Expression Regulates Cardiac Function and Longevity
- 2019
- RNA Sequencing
- Animal
- Circulation Research
- 15.862
Melatonin suppresses milk fat synthesis by inhibiting the mTOR signaling pathway via the MT1 receptor in bovine mammary epithelial cells
- 2019
- RNA Sequencing
- Animal
- Journal of pineal research
- 15.211
Hematopoietic PBX-interacting protein mediates cartilage degeneration during the pathogenesis of osteoarthritis
- 2019
- RNA Sequencing
- Human
- Nature Communications
- 12.353
Therapeutic role of miR-19a/19b in cardiac regeneration and protection from myocardial infarction
- 2019
- RNA Sequencing
- Animal
- Nature Communications
- 12.353
The prostate cancer risk variant rs55958994 regulates multiple gene expression through extreme long-range chromatin interaction to control tumor progression
- 2019
- RNA Sequencing
- Human
- Science Advances
- 11.804
Spliceosome disassembly factors ILP1 and NTR1 promote miRNA biogenesis in Arabidopsis thaliana
- 2019
- small RNA Sequencing
- Plant
- Nucleic Acids Research
- 11.147
HLA‐B*35:01 Allele Is a Potential Biomarker for Predicting Polygonum multiflorum–Induced Liver Injury in Humans
- 2019
- Target Region Sequencing
- Human
- Hepatology
- 14.079
Germline genetic patterns underlying familial rheumatoid arthritis, systemic lupus erythematosus and primary Sjögren’s syndrome highlight T cell-initiated autoimmunity
- 2019
- Whole Exome Sequencing
- Human
- Annals of The Rheumatic Diseases
- 14.299
Recurrent GNAQ mutation encoding T96S in natural killer/T cell lymphoma
- 2019
- Whole Exome Sequencing
- Human
- Nature Communications
- 11.878
Phylogenomics Reveals an Ancient Hybrid Origin of the Persian Walnut
- 2019
- Whole Genome Sequencing
- Plant
- Molecular Biology and Evolution
- 14.797
Development and Genome Sequencing of a Laboratory-Inbred Miniature Pig Facilitates Study of Human Diabetic Disease
- 2019
- Whole Genome Sequencing
- Animal
- iScience
Clam genome sequence clarifies the molecular basis of its benthic adaptation and extraordinary shell color diversity
- 2019
- Whole Genome Sequencing
- Animal
- iScience
Proteomics identifies new therapeutic targets of early-stage hepatocellular carcinoma
- 2019
- Whole Genome Sequencing
- Human
- nature
- 41.577
Genomic Sequencing Identifies WNK2 as a Driver in hepatocellular carcinoma and a Risk Factor for Early Recurrence
- 2019
- Whole Genome Sequencing
- Human
- Journal of Hepatology
- 18.946
The allotetraploid origin and asymmetrical genome evolution of common carp Cyprinus carpio
- 2019
- Whole Genome Sequencing
- Animal
- Acta Pharmaceutica Sinica B
- 12.353
Comparative Population Genomics of Bread Wheat (Triticum aestivum) Reveals Its Cultivation and Breeding History in China.
- 2019
- Whole Genome Sequencing
- Plant
- BioRxiv
Molecular mechanisms of cell death: central implication of ATP synthase in mitochondrial permeability transition
- 2018
- 16S/18S/ITS Amplicon Metagenomic Sequencing
- Human
- Nature Communications
- 12.124
The Gastrodia elata genome provides insights into plant adaptation to heterotrophy
- 2018
- De novo Sequencing
- Plant
- Nature Communications
- 12.353
A genome for gnetophytes and early evolution of seed plants
- 2018
- De novo Sequencing
- Plant
- Nature Plants
- 10.3
Self-Recognition of an Inducible Host lncRNA by RIG-I Feedback Restricts Innate Immune Response
- 2018
- Isoform Sequencing
- Animal
- Cell
- 31.398
RNA N6-methyladenosine methyltransferase-like 3 promotes liver cancer progression through YTHDF2-dependent posttranscriptional silencing of SOCS2.
- 2018
- meRIP-seq
- Human
- Hepatology
- 13.246
The RNA binding protein SORBS2 suppresses metastatic colonization of ovarian cancer by stabilizing tumor-suppressive immunomodulatory transcripts
- 2018
- RNA Sequencing
- Human
- Genome Biology
- 11.908
Pold3 is required for genomic stability and telomere integrity in embryonic stem cells and meiosis
- 2018
- RNA Sequencing
- Animal
- Nucleic Acids Research
- 10.16
Mutational Landscape of Secondary Glioblastoma Guides MET-Targeted Trial in Brain Tumor
- 2018
- Whole Exome Sequencing
- Human
- Cell
- 31.398
Germline BMP9 mutation causes idiopathic pulmonary arterial hypertension
- 2018
- Whole Exome Sequencing
- Human
- European Respiratory journal
- 12.242
Whole-exome sequencing reveals the origin and evolution of hepato-cholangiocarcinoma
- 2018
- Whole Exome Sequencing
- Human
- Nature Communications
- 12.124
A mapping framework of competition–cooperation QTLs that drive community dynamics
- 2018
- Whole Genome Sequencing
- Microbial
- NATURE COMMUNICATIONS
- 12.353
Resequencing core collection of upland cotton (Gossypium hirsutum) identifies genomic variation and loci influencing quality and yield of fiber
- 2018
- Whole Genome Sequencing
- Plant
- Nature Genetics
- 27.959
Genetic variation in PTPN1 contributes to Metabolic Adaptation to High-Altitude Hypoxia in Tibetan Migratory Locusts
- 2018
- Whole Genome Sequencing
- Animal
- Nature Communications
- 12.353
Large-scale gene losses underlie the genome evolution of parasitic plant Cuscuta australis
- 2018
- Whole Genome Sequencing
- Plant
- Nature Communications
- 12.124
Continental-scale pollution of estuaries with antibiotic resistance genes
- 2017
- 16S/18S/ITS Amplicon Metagenomic Sequencing
- Microbial
- Nature Microbiology
- 14.182
The microbiota maintain homeostasis of liver-resident γδT-17 cells in a lipid antigen/CD1d-dependent manner
- 2017
- 16S/18S/ITS Amplicon Metagenomic Sequencing
- Microbial
- Nature Communications
- 11.329
A Natural Allele of a Transcription Factor in Rice Confers Broad-Spectrum Blast Resistance
- 2017
- ChIP-seq
- Plant
- Cell
- 30.41
Scallop genome provides insights into evolution of bilaterian karyotype and development
- 2017
- De novo Sequencing
- Animal
- Nature Ecology & Evolution
The Apostasia genome and the evolution of orchids
- 2017
- De novo Sequencing
- Plant
- Nature
- 40.137
Scallop genome reveals molecular adaptations to semi-sessile life and neurotoxins
- 2017
- De novo Sequencing
- Animal
- Nature Communications
- 12.124
The Aegilops tauschiigenome reveals multipleimpacts of transposons
- 2017
- De novo Sequencing
- Plant
- Nature Plants
- 10.3
Lineage-specific functions of TET1 in the postimplantation mouse embryo
- 2017
- Oxidative Bisulfite Sequencing (oxBS)
- Animal
- Nature Genetics
- 27.959
Genomic analyses of primitive, wild and cultivated citrus provide insights into asexual reproduction
- 2017
- Pan Genome
- Plant
- Nature Genetics
- 27.959
Simultaneous evolutionary expansion and constraint of genomic heterogeneity in multifocal lung cancer
- 2017
- Whole Exome Sequencing
- Human
- Nature Communications
- 12.124
Genetic Alterations in Esophageal Tissues From Squamous Dysplasia to Carcinoma
- 2017
- Whole Genome Sequencing
- Human
- Gastroenterology
- 18.392
SIRT6 Controls Hematopoietic Stem Cell Homeostasis through Epigenetic Regulation of Wnt Signaling
- 2016
- RNA Sequencing
- Animal
- Cell Stem Cell
- 22.268
Genome-wide A-to-I RNA editing in fungi independent of ADAR enzymes
- 2016
- RNA Sequencing
- Microbial
- Genome Research
- 14.63
Single-cell exome sequencing identifies mutations in KCP, LOC440040, and LOC440563 as drivers in renal cell carcinoma stem cells
- 2016
- Whole Exome Sequencing
- Human
- Cell Research
- 15.606
Biallelic SUN5 Mutations Cause Autosomal-Recessive Acephalic Spermatozoa Syndrome
- 2016
- Whole Exome Sequencing
- Human
- American Journal of Human Genetics
- 10.794
The microbiota maintain homeostasis of liver-resident γδT-17 cells in a lipid antigen/CD1d-dependent manner
- 2016
- Whole Genome Sequencing
- Human
- Nature
- 38.138
DNA ethylation and chromatin accessibility profiling of mouse and human fetal germ cells
- 2016
- Whole Genome Sequencing
- Human
- Cell Research
- 14.812
Comprehensive Variation Discovery and Recovery of Missing Sequence in the Pig Genome using Multiple De Novo Assemblies
- 2016
- Whole Genome Sequencing
- Animal
- Genome Research
- 14.381
Population genomics reveals low genetic diversity and adaptation to hypoxia in snub-nosed monkeys
- 2016
- Whole Genome Sequencing
- Animal
- Molecular Biology & Evolution
- 13.649
Whole-genome sequencing of native sheep provides insights into rapid adaptations to extreme environments
- 2016
- Whole Genome Sequencing
- Animal
- Molecular Biology & Evolution
- 13.649
History and temperate adaptation of the honey bee subspecies Apis mellifera sinisxinyuan n. ssp.
- 2016
- Whole Genome Sequencing
- Animal
- Molecular Biology & Evolution
- 13.649
Comprehensive variation discovery and recovery of missing sequence in the pig genome using multiple de novo assemblies
- 2016
- Whole Genome Sequencing
- Animal
- Genome Research
- 11.351
Sequencing of allotetraploid cotton (Gossypium hirsutum L. acc. TM-1) provides a resource for fiber improvement
- 2015
- De novo Sequencing
- Plant
- Nature Biotechnology
- 41.514
Integration of Hippo signalling and the unfolded protein response to restrain liver overgrowth and tumorigenesis
- 2015
- RNA Sequencing
- Animal
- Nature Communications
- 11.47
Whole-genome sequencing of the snub-nosed monkey provides insights into folivory and evolutionary history
- 2014
- De novo Sequencing
- Animal
- Nature Genetics
- 29.352
De novo assembly of soybean wild relatives for pan-genome analysis of diversity and agronomic traits
- 2014
- Pan Genome
- Plant
- Nature Biotechnology
- 41.514
RNA-seq of 272 gliomas revealed a novel, recurrent PTPRZ1-MET fusion transcript in secondary glioblastomas
- 2014
- RNA Sequencing
- Human
- Genome Research
- 14.63
Whole-genome analysis of 5-hydroxymethylcytosine and 5-methylcytosine at base resolution in the human brain
- 2014
- Whole Genome Bisulfite Sequencing (WGBS)
- Human
- Genome Biology
- 10.81
Genomic analyses identify distinct patterns of selection in domesticated pigs and Tibetan wile boars
- 2013
- De novo Sequencing
- Animal
- Nature Genetics
- 29.65
Ground tit genome reveals avian adaptation to living at high altitudes in the Tibetan plateau
- 2013
- De novo Sequencing
- Animal
- Nature Communications
- 10.74
Single-cell RNA-Seq profiling of human preimplantation embryos and embryonic stem cells
- 2013
- RNA Sequencing
- Human
- Nature Structural & Molecular Biology
- 11.633
The genetic basis of whilte tigers
- 2013
- Whole Genome Sequencing
- Animal
- Current Biology
- 10.445
Probing Meiotic Recombination and Aneuploidy of Single Sperm Cells by Whole-Genome Sequencing
- 2012
- Whole Genome Sequencing
- Human
- Science
- 31.027
Whole-genome sequencing of Berkshire (European native pig) provides insights into its origin and domestication
- 2012
- Whole Genome Sequencing
- Animal
- Nature Communications
- 10.015
