Request A Quote
Contact us to discuss how we can help you achieve your research goals
Featured Publications

The Application of RNA Sequencing in Systemic Lupus Erythematosus


RNA sequencing (RNA-seq) has emerged as a powerful tool for gene expression analysis, allowing for the comprehensive study of the transcriptome. It has become an essential technique in various research fields, including disease research. Here, we will explore how RNA-seq was applied to investigate the mechanism of synaptic stripping by microglia in a mouse model of lupus. This study, from Nanjing Drum Tower Hospital collaborated with Nanjing University of Chinese Medicine titled, “Neuronal NR4A1 deficiency drives coordinated synaptic stripping by microglia in a mouse model of lupus”, used RNA-seq and other research methods to clarify that synaptic loss is the early pathology of lupus brain injury, and microglia, complement signals and neurons participate in this process.

Download Now