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Technology: Platform

Lab Platform

Novogene has genomic sequencing labs in the US at The University of California at Davis campus, China, Singapore and the UK (Cambridge), with a total area of nearly 20,000 ㎡, including a 2,000 ㎡ GMP facility and a 2,000 ㎡ clinical laboratory. As of 2023, Novogene has established six lab facilities globally and collaborates with over 6,500 global experts, sequencing over 2 million samples annually in our labs worldwide.

Novogene established the Americas Sequencing Center at UC Davis in early 2016, equipped with NovaSeq 6000, HiSeq X Ten, and HiSeq 4000 sequencing platforms, and completed the installation of NovaSeq X Plus in March 2023. This enables us to provide better next-generation sequencing services and analysis for research and clinical customers in North and South America.

Novogene Cambridge Genomic Sequencing Center is the first European sequencing center of Novogene Europe. It was established in May 2018 and moved to Cambridge Science Park in August 2019. The center is now equipped with automated workstations, multiple NovaSeq 6000s and high-performance computing clusters, and has passed GCLP certification. The NovaSeq X Plus system will serve European customers in 2023.

Novogene has also partnered with AITbiotech to launch a Genomics Center in Singapore to provide NGS services in Asia Pacific, the Middle East and Africa.

In China, we use the most efficient technologies from the world’s leading suppliers, including the Illumina NovaSeq 6000, HiSeq, Oxford Nanopore, PacBio Revio/Sequel II system, as well as the upcoming NovaSeq X Plus system. Currently, Tianjin Medical Laboratory has obtained CAP certification, and this world-class facility enables us to provide high-quality clinical sequencing services globally.

Sequencing Platform



NovaSeq X Plus

  • With the NovaSeq X Plus 10B flow cell, we can sequence up to 64 human genomes with 90Gb as short as 24 hours. 
  • 375G raw data per lane, ~3T raw data per Flowcell, and 2 x 150 bp read length.


NovaSeq 6000

  • With the NovaSeq, we are able to sequence up to 64 human genomes with 90Gb and produce 6Tb of data per single run as short as 40 hours.
  • 850G raw data per lane, 3.4T raw data per Flowcell, and 2 x 150 bp read length.
  • 800M raw reads per Flowcell and 2 x 250bp & 2 x 50 bp reads length.


HiSeq 4000 / 2500 / 2000
HiSeq X Ten

  • HiSeq 4000/2500/2000 system specifications: up to 1200 Gb output range, up to 6B reads per run, and 2 x 50 bp, 2 x 100 bp, 2 x 150bp, and 2 x 250 bp read length.
  • Illumina HiSeq X system specifications: 1.6 – 1.8 Tb output range, 5.3 – 6 B reads per run, and 2 x 150 bp max read length.



  • The Revio system adds affordability, high throughput, and ease of use to a foundation of long reads, exceptional accuracy, and direct methylation detection.
  • The Revio system with a 15x increase in throughput over the Sequel II system. The Revio system can provide exceptional accuracy with 90% of bases ≥Q30 and median read accuracy ≥Q30. With a high-density, 25 million ZMW SMRT Cell, up to 4 SMRT Cells in parallel and 24-hour run times, the Revio system delivers 360 Gb of HiFi reads per day.


  • The PacBio Sequel II/IIe platforms can generate longer reads with the high performance ofconsensus accuracy and coverage.
  • With direct access to HiFi reads, the PacBio Sequel IIe platform requires less time on dataprocessing and analysis, and even reduces ~90% in data storage.
  • By introducing 10 PacBio Sequel IIe platforms, Novogene further enhances the long-read sequencingcapacity in the world.



  • The Chromium Controller platform, powered by Next GEM technology, enables integrated analysis ofsingle cells at a massive scale.
  • The key to this technology is the ability to use advanced microfluidics to generate tens of thousands of single-cell partitions, each containing an identifying barcode for downstream analysis in a matter of minutes.



  • Oxford Nanopore Technologies offers real-time, long-read, direct, and large-scale sequencing of DNA or RNA.
  • The PromethION system sequences DNA or RNA by Nanopore reader proteins embedded in an electrically resistant membrane.
  • Ultra-long reads span repeat regions in complicated genomes easily and enhance the accuracy of genome assembly and large structural variation detection enormously.

Computing Platform

Our supercomputing capability allows us to analyze 280,000 whole human genomes per month. This capability aligns with our unsurpassed NGS capacity, enabling us to run many projects of different sizes and still deliver the data to our customers in a timely fashion. Our state-of-the-art platform is comprised of DELL computing nodes with total memory of 410 TB, computing power of up to 1,727 T flops, and Isilon storage capacity of 62 PB. Our storage capacity can expand as our needs grow, ensuring our customers’ data is backed up and available as needed.