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Introduction of Untargeted Metabolomics

Introduction:

Novogene provides extensive untargeted metabolomics solutions, leveraging advanced platforms such as the Thermo Vanquish™ UHPLC and Thermo Q Exactive™ HF-X for high-resolution mass spectrometry. Our services accommodate various sample types including animal tissues, feces, serum/plasma, plant tissue. The experimental workflow includes sample collection, metabolite extraction, LC-MS detection, and comprehensive qualitative and quantitative analysis using multiple databases, including over 170,000 substances and 15,000 reference standards. Our bioinformatics pipeline ensures robust data quality control and in-depth analysis to generate final reports. We are pleased to present this case study demonstrating the application of our untargeted metabolomics expertise in understanding mannose metabolism’s role in anti-tumor immunity.

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