DNA methylation plays an essential role in numerous important biological processes, including retroviral elements silenc- ing, X-chromosome inactivation, genomic imprinting, suppression of repetitive element transcription and transposition, and more. With the advancements in long-read sequencing technology offered by PacBio and Oxford Nanopore Technology, DNA methylation information now can be directly detected from the original DNA strands without the need for sodium bisulfite processing of DNA samples. Along with the high-quality long-reads, the methylation information will be delivered simultaneously. Check this brochure for more details in revealing DNA methylation by long-read sequencing technologies in Novogene!
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