This webinar will present a recent work from Dr. De’s laboratory which indicates that phenotypic plasticity and dynamic, non-genetic intra-tumor heterogeneity modulate both the trajectory of disease progression and adaptive treatment response in UBC.

Learning Objectives:

• Single cell transcriptomics help profile gene expression profiles in thousands of cells from tissues.
• The integrative analysis reveals a key regulatory program underlying transcriptional state dynamics in bladder cancer.
• Transcriptional state dynamics promotes adaptive tumor treatment response in bladder cancer.