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Untargeted Metabolomics

From molecular signals to functional insight

Genomics and transcriptomics tell you what could happen.

Metabolomics shows you what actually happens.

By measuring small molecules that sit at the end of biological regulation, metabolomics captures the functional state of a system: reflecting phenotype, response, and environmental influence in real time.

Untargeted metabolomics. Discover what is changing, before deciding what to focus on

Untargeted metabolomics is a discovery-driven approach designed to reveal broad metabolic differences between groups, without predefined targets.
It is particularly powerful when:

  • the biology is complex or poorly understood
  • multiple pathways may be involved
  • hypotheses are still being formed

This approach allows researchers to identify key metabolites and pathways that drive phenotypic differences, guiding deeper follow-up studies.

Applications of Untargeted metabolomics

Metabolomics is widely used to explore functional changes linked to:

  • disease state, progression, and treatment response
  • host–microbiome interactions
  • stress, adaptation, and environmental response
  • growth, development, and quality-related traits

How to get started with Novogene

We support a range of commonly used samples, including serum and plasma, faecal samples, animal tissues, plant tissues, and other sample types depending on feasibility.

Tell us:

  • what you want to compare
  • the sample type and approximate number
  • whether you are exploring broadly or targeting specific biology

Our team will advise on the most suitable metabolomics approach and next steps. You will receive structured outputs suitable for comparative and exploratory analysis, including quality control summaries and results that support biological interpretation.

Example reports can be shared on request.

Project workflow

Multi-omics integration

Integrate metabolomics with transcriptomics, proteomics, or metagenomics datasets for comprehensive systems-level insights. If you are interested to explore multi-omics integrated solutions, please contact us for more details.