{"id":37018,"date":"2024-03-03T21:58:53","date_gmt":"2024-03-04T05:58:53","guid":{"rendered":"https:\/\/www.novogene.com\/us-en\/?post_type=resources&#038;p=37018"},"modified":"2025-06-09T03:56:58","modified_gmt":"2025-06-09T10:56:58","slug":"setaria-pan-genome-variation-unraveling-the-story-of-domestication","status":"publish","type":"resources","link":"https:\/\/www.novogene.com\/us-en\/resources\/publications\/setaria-pan-genome-variation-unraveling-the-story-of-domestication\/","title":{"rendered":"<i>Setaria<\/i> Pan-Genome Variation: Unraveling the Story of Domestication"},"content":{"rendered":"<div class=\"zuobian\">\n<h5>Introduction:<\/h5>\n<p style=\"margin-top:0;\">Setaria italica (foxtail millet) is an ideal model for C4 photosynthetic crop plants. Despite its favorable traits, genomic diversity and potential for genetic enhancement remain relatively understudied. Through high throughput sequencing, 110 core-set reference-level genomes were assembled, facilitating the establishment of a complete pan-genome and the construction of a graph-based genome for Setaria. Large-scale genetic studies across 68 traits in 13 environments identified potential genes for millet improvement in diverse geographic locations. These findings can inform marker-assisted breeding, genomic selection, and genome editing to expedite crop improvement under various climatic conditions.<\/p>\n<p style=\"display: inline-block;padding: 10px 20px;background-color: #44944a;border-radius: 20px;margin: 0;\"><a class=\"brochure-dllink\" style=\"color: #fff;font-size: 20px;    font-family: 'Merriweather-Bold', Arial;\" view-href=\"https:\/\/www.novogene.com\/us-en\/wp-content\/uploads\/sites\/4\/2024\/03\/Case-Study_PAWGS_Setaria-Pan-Genome-Variation.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Download Now<\/a><\/p>\n<\/div>\n<div class=\"youbian\">\n<p><img decoding=\"async\" src=\"https:\/\/www.novogene.com\/us-en\/wp-content\/uploads\/sites\/4\/2024\/03\/\u5c01\u9762.png\" alt=\"\" \/><\/p>\n<\/div>\n<style>.zuobian {width: 57%;float: left;margin-bottom: 30px;}.youbian {width: 35%;float: left;margin-left: 30px;margin-top:0;}\n@media all and (min-width: 350px) and (max-width: 760px) {.zuobian {width: 100%;}.youbian {width: 80%;}}<\/style>\n","protected":false},"featured_media":37019,"parent":0,"template":"","yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v20.8 (Yoast SEO v20.8) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Setaria Pan-Genome Variation: Unraveling the Story of Domestication - Novogene<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.novogene.com\/us-en\/resources\/publications\/setaria-pan-genome-variation-unraveling-the-story-of-domestication\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Setaria Pan-Genome Variation: Unraveling the Story of Domestication\" \/>\n<meta property=\"og:description\" content=\"Introduction: Setaria italica (foxtail millet) is an ideal model for C4 photosynthetic crop plants. Despite its favorable traits, genomic diversity and potential for genetic enhancement remain relatively understudied. Through high throughput sequencing, 110 core-set reference-level genomes were assembled, facilitating the establishment of a complete pan-genome and the construction of a graph-based genome for Setaria. Large-scale\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.novogene.com\/us-en\/resources\/publications\/setaria-pan-genome-variation-unraveling-the-story-of-domestication\/\" \/>\n<meta property=\"og:site_name\" content=\"Novogene\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/NovogeneAmerica\/\" \/>\n<meta property=\"article:modified_time\" content=\"2025-06-09T10:56:58+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.novogene.com\/us-en\/wp-content\/uploads\/sites\/4\/2024\/03\/\u5c01\u9762-12.png\" \/>\n\t<meta property=\"og:image:width\" content=\"2709\" \/>\n\t<meta property=\"og:image:height\" content=\"1989\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:site\" content=\"@Novogene_Global\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.novogene.com\/us-en\/resources\/publications\/setaria-pan-genome-variation-unraveling-the-story-of-domestication\/\",\"url\":\"https:\/\/www.novogene.com\/us-en\/resources\/publications\/setaria-pan-genome-variation-unraveling-the-story-of-domestication\/\",\"name\":\"Setaria Pan-Genome Variation: Unraveling the Story of Domestication - Novogene\",\"isPartOf\":{\"@id\":\"https:\/\/www.novogene.com\/us-en\/#website\"},\"datePublished\":\"2024-03-04T05:58:53+00:00\",\"dateModified\":\"2025-06-09T10:56:58+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/www.novogene.com\/us-en\/resources\/publications\/setaria-pan-genome-variation-unraveling-the-story-of-domestication\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.novogene.com\/us-en\/resources\/publications\/setaria-pan-genome-variation-unraveling-the-story-of-domestication\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.novogene.com\/us-en\/resources\/publications\/setaria-pan-genome-variation-unraveling-the-story-of-domestication\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/www.novogene.com\/us-en\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Resources\",\"item\":\"https:\/\/www.novogene.com\/us-en\/resources\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"Setaria Pan-Genome Variation: Unraveling the Story of Domestication\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.novogene.com\/us-en\/#website\",\"url\":\"https:\/\/www.novogene.com\/us-en\/\",\"name\":\"Novogene\",\"description\":\"USA Based Lab Guaranteed Data Security\",\"publisher\":{\"@id\":\"https:\/\/www.novogene.com\/us-en\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.novogene.com\/us-en\/?s={search_term_string}\"},\"query-input\":\"required name=search_term_string\"}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/www.novogene.com\/us-en\/#organization\",\"name\":\"Novogene\",\"url\":\"https:\/\/www.novogene.com\/us-en\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.novogene.com\/us-en\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/www.novogene.com\/us-en\/wp-content\/uploads\/sites\/4\/2020\/05\/20200506113246.png\",\"contentUrl\":\"https:\/\/www.novogene.com\/us-en\/wp-content\/uploads\/sites\/4\/2020\/05\/20200506113246.png\",\"width\":941,\"height\":269,\"caption\":\"Novogene\"},\"image\":{\"@id\":\"https:\/\/www.novogene.com\/us-en\/#\/schema\/logo\/image\/\"},\"sameAs\":[\"https:\/\/www.facebook.com\/NovogeneAmerica\/\",\"https:\/\/twitter.com\/Novogene_Global\",\"https:\/\/www.linkedin.com\/company\/novogene\/\",\"https:\/\/www.youtube.com\/c\/NovogeneGlobal\"]}]}<\/script>\n<!-- \/ Yoast SEO Premium plugin. -->","yoast_head_json":{"title":"Setaria Pan-Genome Variation: Unraveling the Story of Domestication - Novogene","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.novogene.com\/us-en\/resources\/publications\/setaria-pan-genome-variation-unraveling-the-story-of-domestication\/","og_locale":"en_US","og_type":"article","og_title":"Setaria Pan-Genome Variation: Unraveling the Story of Domestication","og_description":"Introduction: Setaria italica (foxtail millet) is an ideal model for C4 photosynthetic crop plants. 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