{"id":36810,"date":"2023-10-30T22:27:44","date_gmt":"2023-10-31T05:27:44","guid":{"rendered":"https:\/\/www.novogene.com\/us-en\/?post_type=resources&#038;p=36810"},"modified":"2025-06-09T03:45:26","modified_gmt":"2025-06-09T10:45:26","slug":"brochure-comprehensive-dna-methylation-calling-by-long-read-sequencing-in-novogene-introduction","status":"publish","type":"resources","link":"https:\/\/www.novogene.com\/us-en\/resources\/brochure\/brochure-comprehensive-dna-methylation-calling-by-long-read-sequencing-in-novogene-introduction\/","title":{"rendered":"Brochure-Comprehensive DNA Methylation Calling by Long-read Sequencing in Novogene Introduction"},"content":{"rendered":"<div class=\"zuobian\">\n<h5>Introduction:<\/h5>\n<p style=\"margin-top:0;\">DNA methylation plays an essential role in numerous important biological processes, including retroviral elements silenc- ing, X-chromosome inactivation, genomic imprinting, suppression of repetitive element transcription and transposition, and more. With the advancements in long-read sequencing technology offered by PacBio and Oxford Nanopore Technology, DNA methylation information now can be directly detected from the original DNA strands without the need for sodium bisulfite processing of DNA samples.  Along with the high-quality long-reads, the methylation information will be delivered simultaneously.  Check this brochure for more details in revealing DNA methylation by long-read sequencing technologies in Novogene!<\/p>\n<p style=\"display: inline-block;padding: 10px 20px;background-color: #44944a;border-radius: 20px;margin: 0;\"><a class=\"brochure-dllink\" style=\"color: #fff;font-size: 20px;    font-family: 'Merriweather-Bold', Arial;\" view-href=\"https:\/\/www.novogene.com\/us-en\/wp-content\/uploads\/sites\/4\/2023\/10\/Comprehensive-DNA-Methylation-Calling-by-Long-read-Sequencing-in-Novogene.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Download Now<\/a><\/p>\n<\/div>\n<div class=\"youbian\">\n<p><img decoding=\"async\" style=\"border:1px solid #000;\" src=\"https:\/\/www.novogene.com\/us-en\/wp-content\/uploads\/sites\/4\/2023\/10\/Comprehensive-DNA-Methylation-Calling-by-Long-read-Sequencing-in-Novogene.png\" alt=\"\" \/><\/p>\n<\/div>\n<style>.zuobian {width: 57%;float: left;margin-bottom: 30px;}.youbian {width: 35%;float: left;margin-left: 30px;margin-top:0;}\n@media all and (min-width: 350px) and (max-width: 760px) {.zuobian {width: 100%;}.youbian {width: 80%;}}<\/style>\n","protected":false},"featured_media":36811,"parent":0,"template":"","yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v20.8 (Yoast SEO v20.8) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Brochure-Comprehensive DNA Methylation Calling by Long-read Sequencing in Novogene Introduction - Novogene<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.novogene.com\/us-en\/resources\/brochure\/brochure-comprehensive-dna-methylation-calling-by-long-read-sequencing-in-novogene-introduction\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Brochure-Comprehensive DNA Methylation Calling by Long-read Sequencing in Novogene Introduction\" \/>\n<meta property=\"og:description\" content=\"Introduction: DNA methylation plays an essential role in numerous important biological processes, including retroviral elements silenc- ing, X-chromosome inactivation, genomic imprinting, suppression of repetitive element transcription and transposition, and more. With the advancements in long-read sequencing technology offered by PacBio and Oxford Nanopore Technology, DNA methylation information now can be directly detected from the original\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.novogene.com\/us-en\/resources\/brochure\/brochure-comprehensive-dna-methylation-calling-by-long-read-sequencing-in-novogene-introduction\/\" \/>\n<meta property=\"og:site_name\" content=\"Novogene\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/NovogeneAmerica\/\" \/>\n<meta property=\"article:modified_time\" content=\"2025-06-09T10:45:26+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.novogene.com\/us-en\/wp-content\/uploads\/sites\/4\/2023\/10\/Comprehensive-DNA-Methylation-Calling-by-Long-read-Sequencing-in-Novogene-797x1024.png\" \/>\n\t<meta property=\"og:image:width\" content=\"797\" \/>\n\t<meta property=\"og:image:height\" content=\"1024\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:site\" content=\"@Novogene_Global\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.novogene.com\/us-en\/resources\/brochure\/brochure-comprehensive-dna-methylation-calling-by-long-read-sequencing-in-novogene-introduction\/\",\"url\":\"https:\/\/www.novogene.com\/us-en\/resources\/brochure\/brochure-comprehensive-dna-methylation-calling-by-long-read-sequencing-in-novogene-introduction\/\",\"name\":\"Brochure-Comprehensive DNA Methylation Calling by Long-read Sequencing in Novogene Introduction - 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