{"id":36287,"date":"2023-07-26T02:30:27","date_gmt":"2023-07-26T09:30:27","guid":{"rendered":"https:\/\/www.novogene.com\/us-en\/?post_type=resources&#038;p=36287"},"modified":"2023-10-23T00:40:17","modified_gmt":"2023-10-23T07:40:17","slug":"the-application-of-rna-sequencing-in-systemic-lupus-erythematosus","status":"publish","type":"resources","link":"https:\/\/www.novogene.com\/us-en\/resources\/publications\/the-application-of-rna-sequencing-in-systemic-lupus-erythematosus\/","title":{"rendered":"The Application of RNA Sequencing in Systemic Lupus Erythematosus"},"content":{"rendered":"<div class=\"zuobian\">\n<h5>Introduction:<\/h5>\n<p style=\"margin-top:0;\">RNA sequencing (RNA-seq) has emerged as a powerful tool for gene expression analysis, allowing for the comprehensive study of the transcriptome. It has become an essential technique in various research fields, including disease research. Here, we will explore how RNA-seq was applied to investigate the mechanism of synaptic stripping by microglia in a mouse model of lupus. This study, from Nanjing Drum Tower Hospital collaborated with Nanjing University of Chinese Medicine titled, &#8220;Neuronal NR4A1 deficiency drives coordinated synaptic stripping by microglia in a mouse model of lupus&#8221;, used RNA-seq and other research methods to clarify that synaptic loss is the early pathology of lupus brain injury, and microglia, complement signals and neurons participate in this process.<\/p>\n<p style=\"display: inline-block;padding: 10px 20px;background-color: #44944a;border-radius: 20px;margin: 0;\"><a class=\"brochure-dllink\" style=\"color: #fff;font-size: 20px;    font-family: 'Merriweather-Bold', Arial;\" view-href=\"https:\/\/www.novogene.com\/us-en\/wp-content\/uploads\/sites\/4\/2023\/10\/The-Application-of-RNA-Sequencing-in-Systemic-Lupus-Erythematosus.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Download Now<\/a><\/p>\n<\/div>\n<div class=\"youbian\">\n<p><img decoding=\"async\" src=\"https:\/\/www.novogene.com\/us-en\/wp-content\/uploads\/sites\/4\/2023\/07\/Introduction\u9875\u5c01\u9762-1.png\" alt=\"\" \/><\/p>\n<\/div>\n<style>.zuobian {width: 57%;float: left;margin-bottom: 30px;}.youbian {width: 35%;float: left;margin-left: 30px;margin-top:0;}\n@media all and (min-width: 350px) and (max-width: 760px) {.zuobian {width: 100%;}.youbian {width: 80%;}}<\/style>\n","protected":false},"featured_media":36288,"parent":0,"template":"","yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v20.8 (Yoast SEO v20.8) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>The Application of RNA Sequencing in Systemic Lupus Erythematosus - Novogene<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.novogene.com\/us-en\/resources\/publications\/the-application-of-rna-sequencing-in-systemic-lupus-erythematosus\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"The Application of RNA Sequencing in Systemic Lupus Erythematosus\" \/>\n<meta property=\"og:description\" content=\"Introduction: RNA sequencing (RNA-seq) has emerged as a powerful tool for gene expression analysis, allowing for the comprehensive study of the transcriptome. It has become an essential technique in various research fields, including disease research. Here, we will explore how RNA-seq was applied to investigate the mechanism of synaptic stripping by microglia in a mouse\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.novogene.com\/us-en\/resources\/publications\/the-application-of-rna-sequencing-in-systemic-lupus-erythematosus\/\" \/>\n<meta property=\"og:site_name\" content=\"Novogene\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/NovogeneAmerica\/\" \/>\n<meta property=\"article:modified_time\" content=\"2023-10-23T07:40:17+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.novogene.com\/us-en\/wp-content\/uploads\/sites\/4\/2023\/07\/\u7f51\u9875\u9884\u89c8\u56fe.png\" \/>\n\t<meta property=\"og:image:width\" content=\"1448\" \/>\n\t<meta property=\"og:image:height\" content=\"1063\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:site\" content=\"@Novogene_Global\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.novogene.com\/us-en\/resources\/publications\/the-application-of-rna-sequencing-in-systemic-lupus-erythematosus\/\",\"url\":\"https:\/\/www.novogene.com\/us-en\/resources\/publications\/the-application-of-rna-sequencing-in-systemic-lupus-erythematosus\/\",\"name\":\"The Application of RNA Sequencing in Systemic Lupus Erythematosus - Novogene\",\"isPartOf\":{\"@id\":\"https:\/\/www.novogene.com\/us-en\/#website\"},\"datePublished\":\"2023-07-26T09:30:27+00:00\",\"dateModified\":\"2023-10-23T07:40:17+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/www.novogene.com\/us-en\/resources\/publications\/the-application-of-rna-sequencing-in-systemic-lupus-erythematosus\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.novogene.com\/us-en\/resources\/publications\/the-application-of-rna-sequencing-in-systemic-lupus-erythematosus\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.novogene.com\/us-en\/resources\/publications\/the-application-of-rna-sequencing-in-systemic-lupus-erythematosus\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/www.novogene.com\/us-en\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Resources\",\"item\":\"https:\/\/www.novogene.com\/us-en\/resources\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"The Application of RNA Sequencing in Systemic Lupus Erythematosus\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.novogene.com\/us-en\/#website\",\"url\":\"https:\/\/www.novogene.com\/us-en\/\",\"name\":\"Novogene\",\"description\":\"USA Based Lab Guaranteed Data Security\",\"publisher\":{\"@id\":\"https:\/\/www.novogene.com\/us-en\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.novogene.com\/us-en\/?s={search_term_string}\"},\"query-input\":\"required name=search_term_string\"}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/www.novogene.com\/us-en\/#organization\",\"name\":\"Novogene\",\"url\":\"https:\/\/www.novogene.com\/us-en\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.novogene.com\/us-en\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/www.novogene.com\/us-en\/wp-content\/uploads\/sites\/4\/2020\/05\/20200506113246.png\",\"contentUrl\":\"https:\/\/www.novogene.com\/us-en\/wp-content\/uploads\/sites\/4\/2020\/05\/20200506113246.png\",\"width\":941,\"height\":269,\"caption\":\"Novogene\"},\"image\":{\"@id\":\"https:\/\/www.novogene.com\/us-en\/#\/schema\/logo\/image\/\"},\"sameAs\":[\"https:\/\/www.facebook.com\/NovogeneAmerica\/\",\"https:\/\/twitter.com\/Novogene_Global\",\"https:\/\/www.linkedin.com\/company\/novogene\/\",\"https:\/\/www.youtube.com\/c\/NovogeneGlobal\"]}]}<\/script>\n<!-- \/ Yoast SEO Premium plugin. -->","yoast_head_json":{"title":"The Application of RNA Sequencing in Systemic Lupus Erythematosus - Novogene","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.novogene.com\/us-en\/resources\/publications\/the-application-of-rna-sequencing-in-systemic-lupus-erythematosus\/","og_locale":"en_US","og_type":"article","og_title":"The Application of RNA Sequencing in Systemic Lupus Erythematosus","og_description":"Introduction: RNA sequencing (RNA-seq) has emerged as a powerful tool for gene expression analysis, allowing for the comprehensive study of the transcriptome. 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