{"id":35277,"date":"2022-12-11T19:10:02","date_gmt":"2022-12-12T03:10:02","guid":{"rendered":"https:\/\/www.novogene.com\/us-en\/?post_type=resources&#038;p=35277"},"modified":"2025-06-09T04:00:07","modified_gmt":"2025-06-09T11:00:07","slug":"third-generation-sequencing-guide-to-whole-genome-re-sequencing","status":"publish","type":"resources","link":"https:\/\/www.novogene.com\/us-en\/resources\/event\/third-generation-sequencing-guide-to-whole-genome-re-sequencing\/","title":{"rendered":"Third-Generation Sequencing Guide to Whole Genome Re-sequencing"},"content":{"rendered":"<div style=\"display: flex;margin-top: 40px;flex-wrap: wrap; \">\n<div class=\"web-left\">\n      <strong>Introduction:<\/strong><\/p>\n<p>Whole Genome Re-sequencing offers the full spectrum of genetic variation of an organism (i.e. human, plant, animal or microbe) through the alignment of sequenced reads of entire genome to known genomic sequences. This genomics research further helped to refine our understandings on evolution, adaptation, and disease. It has been dominated by Next-Generation Sequencing (NGS) technologies for decades, driven by its superiority in producing highly accurate (>99.9%) short sequencing reads, on a massive scale with cost-effectiveness. Yet, the suboptimal application of it in many instances inevitably revealed two major shortcomings: GC biased coverage and limited read length to span highly complex or repetitive area. <\/p>\n<p><\/p>\n<p style=\"margin-bottom: 10px;margin-top:0\"><strong>Learning Objectives:<\/strong><\/p>\n<ul>\n<li style=\"margin-bottom: 10px;font-family: 'Montserrat-Regular', Arial;\">Introduction of Third-Generation Sequencing platforms &#8211; PacBio and Nanopore, per principle, superiority compared to NGS and application potentials in biological and biomedical researches <\/li>\n<li style=\"margin-bottom: 10px;font-family: 'Montserrat-Regular', Arial;\">Our optimized Whole Genome Re-sequencing pipeline on PacBio and Nanopore, from sample submission guidelines to bioinformatic analysis<\/li>\n<li style=\"margin-bottom: 10px;font-family: 'Montserrat-Regular', Arial;\">Novogene-powered Case study Share exemplifies how this service is practically applied in genomics<\/li>\n<\/ul><\/div>\n<div class=\"web-right\" style=\"\" >\n<div style=\"padding:0 20px;\">\n<div>\n<a class=\"video-\" style=\"display: block;\" text=\"https:\/\/www.youtube.com\/embed\/F7NC9mmX2ZY\"><img decoding=\"async\" style=\"width: 100%;margin-top: 20px;\" src=\"https:\/\/www.novogene.com\/us-en\/wp-content\/uploads\/sites\/4\/2022\/12\/Silu-Li.png\"><\/a>\n         <\/div>\n<p style=\"margin-bottom: 10px;\"><strong>Speakers:<\/strong><\/p>\n<p class=\"video-\" style=\"margin-bottom: 0;margin-top:0\">Silu Li, Product Specialist\uff0cNovogene Corporation Inc<\/p>\n<\/p><\/div>\n<\/p><\/div>\n<\/div>\n<style>.web-left {width: 35%;margin-right: 20px;}.web-right {width:60%;background-color: #f0f0f0;}@media screen and (min-width: 375px) and (max-width: 550px){.web-left {width: 100%;}.web-right {width: 100%;}}<\/style>\n","protected":false},"featured_media":0,"parent":0,"template":"","yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v20.8 (Yoast SEO v20.8) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Third-Generation Sequencing Guide to Whole Genome Re-sequencing - Novogene<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.novogene.com\/us-en\/resources\/event\/third-generation-sequencing-guide-to-whole-genome-re-sequencing\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Third-Generation Sequencing Guide to Whole Genome Re-sequencing\" \/>\n<meta property=\"og:description\" content=\"Introduction: Whole Genome Re-sequencing offers the full spectrum of genetic variation of an organism (i.e. human, plant, animal or microbe) through the alignment of sequenced reads of entire genome to known genomic sequences. This genomics research further helped to refine our understandings on evolution, adaptation, and disease. It has been dominated by Next-Generation Sequencing (NGS)\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.novogene.com\/us-en\/resources\/event\/third-generation-sequencing-guide-to-whole-genome-re-sequencing\/\" \/>\n<meta property=\"og:site_name\" content=\"Novogene\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/NovogeneAmerica\/\" \/>\n<meta property=\"article:modified_time\" content=\"2025-06-09T11:00:07+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.novogene.com\/us-en\/wp-content\/uploads\/sites\/4\/2022\/12\/Silu-Li.png\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:site\" content=\"@Novogene_Global\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.novogene.com\/us-en\/resources\/event\/third-generation-sequencing-guide-to-whole-genome-re-sequencing\/\",\"url\":\"https:\/\/www.novogene.com\/us-en\/resources\/event\/third-generation-sequencing-guide-to-whole-genome-re-sequencing\/\",\"name\":\"Third-Generation Sequencing Guide to Whole Genome Re-sequencing - Novogene\",\"isPartOf\":{\"@id\":\"https:\/\/www.novogene.com\/us-en\/#website\"},\"datePublished\":\"2022-12-12T03:10:02+00:00\",\"dateModified\":\"2025-06-09T11:00:07+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/www.novogene.com\/us-en\/resources\/event\/third-generation-sequencing-guide-to-whole-genome-re-sequencing\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.novogene.com\/us-en\/resources\/event\/third-generation-sequencing-guide-to-whole-genome-re-sequencing\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.novogene.com\/us-en\/resources\/event\/third-generation-sequencing-guide-to-whole-genome-re-sequencing\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/www.novogene.com\/us-en\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Resources\",\"item\":\"https:\/\/www.novogene.com\/us-en\/resources\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"Third-Generation Sequencing Guide to Whole Genome Re-sequencing\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.novogene.com\/us-en\/#website\",\"url\":\"https:\/\/www.novogene.com\/us-en\/\",\"name\":\"Novogene\",\"description\":\"USA Based Lab Guaranteed Data Security\",\"publisher\":{\"@id\":\"https:\/\/www.novogene.com\/us-en\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.novogene.com\/us-en\/?s={search_term_string}\"},\"query-input\":\"required name=search_term_string\"}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/www.novogene.com\/us-en\/#organization\",\"name\":\"Novogene\",\"url\":\"https:\/\/www.novogene.com\/us-en\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.novogene.com\/us-en\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/www.novogene.com\/us-en\/wp-content\/uploads\/sites\/4\/2020\/05\/20200506113246.png\",\"contentUrl\":\"https:\/\/www.novogene.com\/us-en\/wp-content\/uploads\/sites\/4\/2020\/05\/20200506113246.png\",\"width\":941,\"height\":269,\"caption\":\"Novogene\"},\"image\":{\"@id\":\"https:\/\/www.novogene.com\/us-en\/#\/schema\/logo\/image\/\"},\"sameAs\":[\"https:\/\/www.facebook.com\/NovogeneAmerica\/\",\"https:\/\/twitter.com\/Novogene_Global\",\"https:\/\/www.linkedin.com\/company\/novogene\/\",\"https:\/\/www.youtube.com\/c\/NovogeneGlobal\"]}]}<\/script>\n<!-- \/ Yoast SEO Premium plugin. -->","yoast_head_json":{"title":"Third-Generation Sequencing Guide to Whole Genome Re-sequencing - Novogene","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.novogene.com\/us-en\/resources\/event\/third-generation-sequencing-guide-to-whole-genome-re-sequencing\/","og_locale":"en_US","og_type":"article","og_title":"Third-Generation Sequencing Guide to Whole Genome Re-sequencing","og_description":"Introduction: Whole Genome Re-sequencing offers the full spectrum of genetic variation of an organism (i.e. human, plant, animal or microbe) through the alignment of sequenced reads of entire genome to known genomic sequences. 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