{"id":34528,"date":"2022-09-01T02:20:50","date_gmt":"2022-09-01T09:20:50","guid":{"rendered":"https:\/\/www.novogene.com\/us-en\/?post_type=resources&#038;p=34528"},"modified":"2025-06-09T04:21:18","modified_gmt":"2025-06-09T11:21:18","slug":"10x-single-cell-rna-seq-case-study-on-gallbladder-cancer","status":"publish","type":"resources","link":"https:\/\/www.novogene.com\/us-en\/resources\/brochure\/10x-single-cell-rna-seq-case-study-on-gallbladder-cancer\/","title":{"rendered":"10x Single-cell RNA-seq case study on gallbladder cancer"},"content":{"rendered":"<div class=\"zuobian\">\n<h5>Introduction:<\/h5>\n<p style=\"margin-top:0;\">Gallbladder carcinoma (GBC) is the most common cancer of the biliary tract and the sixth most common type of gastrointestinal cancer worldwide. Growing evidence suggests that genomic alterations acquired during oncogenesis help tumor cells to escape immune surveillance. ErbB signaling is the most extensively mutated pathway that mediates anti-tumor immunity. This study took advantage of the newly created scRNA-seq technology to test the hypothesis that individual cellular components of the tumor microenvironment (TME) in GBC function differentially to participate in ErbB pathway mutation-dependent tumor progression.<\/p>\n<p style=\"display: inline-block;padding: 10px 20px;background-color: #44944a;border-radius: 20px;margin: 0;\"><a class=\"brochure-dllink\" style=\"color: #fff;font-size: 20px;    font-family: 'Merriweather-Bold', Arial;\" view-href=\"https:\/\/www.novogene.com\/us-en\/wp-content\/uploads\/sites\/4\/2023\/10\/10x-Single-cell-RNA-seq-case-study-on-gallbladder-cancer.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Download Now<\/a><\/p>\n<\/div>\n<div class=\"youbian\">\n<p ><img decoding=\"async\" src=\"https:\/\/www.novogene.com\/us-en\/wp-content\/uploads\/sites\/4\/2022\/09\/10xscRNA-seq-case-study-MDK-dependent-immunosuppression-20220822_1.png\" alt=\"\" \/><\/p>\n<\/div>\n<style>.zuobian {width: 57%;float: left;margin-bottom: 30px;}.youbian {width: 35%;float: left;margin-left: 30px;margin-top:0;}\n@media all and (min-width: 350px) and (max-width: 760px) {.zuobian {width: 100%;}.youbian {width: 80%;}}<\/style>\n","protected":false},"featured_media":34531,"parent":0,"template":"","yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v20.8 (Yoast SEO v20.8) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>10x Single-cell RNA-seq case study on gallbladder cancer - Novogene<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.novogene.com\/us-en\/resources\/brochure\/10x-single-cell-rna-seq-case-study-on-gallbladder-cancer\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"10x Single-cell RNA-seq case study on gallbladder cancer\" \/>\n<meta property=\"og:description\" content=\"Introduction: Gallbladder carcinoma (GBC) is the most common cancer of the biliary tract and the sixth most common type of gastrointestinal cancer worldwide. Growing evidence suggests that genomic alterations acquired during oncogenesis help tumor cells to escape immune surveillance. ErbB signaling is the most extensively mutated pathway that mediates anti-tumor immunity. This study took advantage\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.novogene.com\/us-en\/resources\/brochure\/10x-single-cell-rna-seq-case-study-on-gallbladder-cancer\/\" \/>\n<meta property=\"og:site_name\" content=\"Novogene\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/NovogeneAmerica\/\" \/>\n<meta property=\"article:modified_time\" content=\"2025-06-09T11:21:18+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.novogene.com\/us-en\/wp-content\/uploads\/sites\/4\/2022\/09\/10xscRNA-seq-case-study-MDK-dependent-immunosuppression-20220822_1.png\" \/>\n\t<meta property=\"og:image:width\" content=\"1313\" \/>\n\t<meta property=\"og:image:height\" content=\"1688\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:site\" content=\"@Novogene_Global\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.novogene.com\/us-en\/resources\/brochure\/10x-single-cell-rna-seq-case-study-on-gallbladder-cancer\/\",\"url\":\"https:\/\/www.novogene.com\/us-en\/resources\/brochure\/10x-single-cell-rna-seq-case-study-on-gallbladder-cancer\/\",\"name\":\"10x Single-cell RNA-seq case study on gallbladder cancer - Novogene\",\"isPartOf\":{\"@id\":\"https:\/\/www.novogene.com\/us-en\/#website\"},\"datePublished\":\"2022-09-01T09:20:50+00:00\",\"dateModified\":\"2025-06-09T11:21:18+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/www.novogene.com\/us-en\/resources\/brochure\/10x-single-cell-rna-seq-case-study-on-gallbladder-cancer\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.novogene.com\/us-en\/resources\/brochure\/10x-single-cell-rna-seq-case-study-on-gallbladder-cancer\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.novogene.com\/us-en\/resources\/brochure\/10x-single-cell-rna-seq-case-study-on-gallbladder-cancer\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/www.novogene.com\/us-en\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Resources\",\"item\":\"https:\/\/www.novogene.com\/us-en\/resources\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"10x Single-cell RNA-seq case study on gallbladder cancer\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.novogene.com\/us-en\/#website\",\"url\":\"https:\/\/www.novogene.com\/us-en\/\",\"name\":\"Novogene\",\"description\":\"USA Based Lab Guaranteed Data Security\",\"publisher\":{\"@id\":\"https:\/\/www.novogene.com\/us-en\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.novogene.com\/us-en\/?s={search_term_string}\"},\"query-input\":\"required name=search_term_string\"}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/www.novogene.com\/us-en\/#organization\",\"name\":\"Novogene\",\"url\":\"https:\/\/www.novogene.com\/us-en\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.novogene.com\/us-en\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/www.novogene.com\/us-en\/wp-content\/uploads\/sites\/4\/2020\/05\/20200506113246.png\",\"contentUrl\":\"https:\/\/www.novogene.com\/us-en\/wp-content\/uploads\/sites\/4\/2020\/05\/20200506113246.png\",\"width\":941,\"height\":269,\"caption\":\"Novogene\"},\"image\":{\"@id\":\"https:\/\/www.novogene.com\/us-en\/#\/schema\/logo\/image\/\"},\"sameAs\":[\"https:\/\/www.facebook.com\/NovogeneAmerica\/\",\"https:\/\/twitter.com\/Novogene_Global\",\"https:\/\/www.linkedin.com\/company\/novogene\/\",\"https:\/\/www.youtube.com\/c\/NovogeneGlobal\"]}]}<\/script>\n<!-- \/ Yoast SEO Premium plugin. -->","yoast_head_json":{"title":"10x Single-cell RNA-seq case study on gallbladder cancer - Novogene","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.novogene.com\/us-en\/resources\/brochure\/10x-single-cell-rna-seq-case-study-on-gallbladder-cancer\/","og_locale":"en_US","og_type":"article","og_title":"10x Single-cell RNA-seq case study on gallbladder cancer","og_description":"Introduction: Gallbladder carcinoma (GBC) is the most common cancer of the biliary tract and the sixth most common type of gastrointestinal cancer worldwide. 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