{"id":15403,"date":"2020-12-01T00:05:44","date_gmt":"2020-12-01T08:05:44","guid":{"rendered":"https:\/\/www.novogene.com\/us-en\/?post_type=resources&p=15403"},"modified":"2025-05-29T03:43:04","modified_gmt":"2025-05-29T10:43:04","slug":"high-throughput-rna-seq-unveil-transcriptome-mystery-at-novogene","status":"publish","type":"resources","link":"https:\/\/www.novogene.com\/us-en\/resources\/blog\/high-throughput-rna-seq-unveil-transcriptome-mystery-at-novogene\/","title":{"rendered":"High Throughput RNA-seq unveils Transcriptome Mystery at Novogene"},"content":{"rendered":"
\n

Transcriptome\u00a0analysis examines the complete set of RNA transcripts in a cell using high-throughput RNA-sequencing (RNA-seq). This valuable tool provides important information on gene function in a cell, a population of cells, or in an organism, that are under a specific set of conditions. RNA-seq identifies all RNA transcripts in a sample, including the regulatory\u00a0miRNA\u00a0and lncRNA transcripts. The sequences obtained by these methods can then be aligned to reference sequences to identify which genes have been transcribed in the sample.<\/p>\n

Novogene\u00a0is a leading genomics solution provider that offers a wide range of\u00a0transcriptome\u00a0sequencing services ranging from mRNA-sequencing to whole\u00a0transcriptome\u00a0analysis. With 29 next-generation sequencing (NGS) -related patents and over 560 research papers,\u00a0Novogene\u00a0is a world leader in next- NGS services.\u00a0Novogene\u2019s services offer comprehensive solutions for the analysis of gene expression quantification and differential gene expression, the identification of novel transcripts, examining alternative splicing and gene fusion events, and more. The company’s\u00a0bioinformaticians\u00a0provide standard and customized data analysis, resulting in publication-ready results.<\/p>\n

The experimental objective should dictate the type of sequencing that is used. For example, mRNA-sequencing (\u00a0mRNA-seq) focuses only on the coding\u00a0RNAs, which make up approximately 2% of the entire\u00a0transcriptome. This type of sequencing is ideal if research focuses only on these coding regions.\u00a0mRNA-seq\u00a0enables researchers to examine the variations in the cellular\u00a0transcriptome\u00a0by looking at the\u00a0mRNA\u00a0expression levels in a biological sample. It is often used to identify or compare gene expression levels between groups.\u00a0Novogene\u2019s\u00a0mRNA-seq\u00a0is performed on the\u00a0Illumina\u00a0NovaSeq\u00a0platforms with paired-end 150\u00a0base pair\u00a0sequencing read length. The sequencing depth varies based on whether a reference genome is available.<\/p>\n

By comparison, whole\u00a0transcriptome\u00a0sequencing (WTS) looks at the set of genes that are transcribed by an organism at any given moment and includes all coding and non-coding RNA transcripts. This competitive approach is particularly useful for understanding what genes\u00a0are\u00a0being transcribed under different conditions. Once the\u00a0transcriptome\u00a0has been sequenced, the information can be used to ascertain which parts of the genome codes for active genes. This can be taken further by sequencing the\u00a0transcriptome\u00a0several times under different conditions or at\u00a0different\u00a0life stages to help understand which genes are involved in which biological processes.\u00a0Novogene\u2019s\u00a0WTS\u00a0service enables researchers to investigate potential\u00a0transcriptional\u00a0and regulatory network mechanisms by enabling an in-depth bioinformatics analysis on all transcripts including\u00a0mRNAs\u00a0and non-coding\u00a0RNAs.<\/p>\n

Aside from\u00a0mRNA-seq\u00a0and\u00a0WTS,\u00a0Novogene\u00a0offers other\u00a0transcriptome\u00a0sequencing services including metatranscriptome analysis which examines the total content of gene transcripts in a\u00a0community,\u00a0such as soil, water, or in the gut, prokaryote RNA-sequencing, and an isoform-sequencing service that can be useful for detecting gene fusion events as well as providing more in-depth transcript annotation.
\nTo improve the accuracy of their next-generation sequencing services further,\u00a0Novogene\u00a0launched a new product named Falcon in March 2020. Falcon is the first intelligent multi-product delivery platform for high-throughput NGS. Falcon promises to offer faster delivery with a more stable quality by eliminating human error and\u00a0increasing efficiency. This platform will provide\u00a0Novogene\u2019s customers with an intelligent and robust service that can process up to\u00a02850\u00a0samples each day. This new platform aims to increase the quality of Novogene\u2019s services and\u00a0meet\u00a0the sequencing requirements of its customers.<\/p>\n

The founder and CEO of Novogene, Dr. Li Ruiqiang said,\u00a0\u201cLeveraging our years of expertise in genomic sequencing has enabled Novogene to develop and launch the first intelligent multi-product NGS delivery platform, which will provide a cutting-edge sequencing solution for customers. As a safe and accurate one-stop ground-breaking solution, Falcon enables faster delivery with a more stable quality. As a leading provider of genomic services and solutions in the world, we want to be better positioned to drive innovation in the industry, to lead the industry in the direction towards becoming digital and automated, to propel the establishment of industry standards, and to eventually achieve intelligent transformation.\u201d<\/p>\n

To get more information about Novogene services, please visit novogene.com\/us-en.
\n<\/i>
\nContact us at here (https:\/\/bit.ly\/33b97Wi). Your dedicated Novogene representative will reach out to you within ONE business day.<\/i> <\/i><\/p>\n

Transcriptome\u00a0analysis examines the complete set of RNA transcripts in a cell using high-throughput RNA-sequencing (RNA-seq). This valuable tool provides important information on gene function in a cell, a population of cells, or in an organism, that are under a specific set of conditions. RNA-seq identifies all RNA transcripts in a sample, including the regulatory\u00a0miRNA\u00a0and lncRNA transcripts. The sequences obtained by these methods can then be aligned to reference sequences to identify which genes have been transcribed in the sample.<\/p>\n

Novogene is a leading genomics solution provider that offers a wide range of transcriptome sequencing services ranging from mRNA-sequencing to whole transcriptome analysis. With 29 next-generation sequencings (NGS) – related patents and over 560 research papers, Novogene is a world leader in next- NGS services. Novogene\u2019s services offer comprehensive solutions for the analysis of gene expression quantification and differential gene expression, the identification of novel transcripts, examining alternative splicing and gene fusion events, and more. The company’s bioinformaticians provide standard and customized data analysis, resulting in publication-ready results.<\/p>\n

The experimental objective should dictate the type of sequencing that is used. For example, mRNA-sequencing (\u00a0mRNA-seq) focuses only on the coding\u00a0RNAs, which make up approximately 2% of the entire\u00a0transcriptome. This type of sequencing is ideal if research focuses only on these coding regions.\u00a0mRNA-seq\u00a0enables researchers to examine the variations in the cellular\u00a0transcriptome\u00a0by looking at the\u00a0mRNA\u00a0expression levels in a biological sample. It is often used to identify or compare gene expression levels between groups.\u00a0Novogene\u2019s\u00a0mRNA-seq\u00a0is performed on the\u00a0Illumina\u00a0NovaSeq\u00a0platforms with paired-end 150\u00a0base pair\u00a0sequencing read length. The sequencing depth varies based on whether a reference genome is available.<\/p>\n

By comparison, whole\u00a0transcriptome\u00a0sequencing (WTS) looks at the set of genes that are transcribed by an organism at any given moment and includes all coding and non-coding RNA transcripts. This competitive approach is particularly useful for understanding what genes\u00a0are\u00a0being transcribed under different conditions. Once the\u00a0transcriptome\u00a0has been sequenced, the information can be used to ascertain which parts of the genome codes for active genes. This can be taken further by sequencing the\u00a0transcriptome\u00a0several times under different conditions or at\u00a0different\u00a0life stages to help understand which genes are involved in which biological processes.\u00a0Novogene\u2019s\u00a0WTS\u00a0service enables researchers to investigate potential\u00a0transcriptional\u00a0and regulatory network mechanisms by enabling an in-depth bioinformatics analysis on all transcripts including\u00a0mRNAs\u00a0and non-coding\u00a0RNAs<\/p>\n

Aside from mRNA-seq and WTS, Novogene offers other transcriptome sequencing services including metatranscriptome analysis which examines the total content of gene transcripts in a community, such as soil, water, or in the gut, prokaryote RNA-sequencing, and an isoform-sequencing service that can be useful for detecting gene fusion events as well as providing more in-depth transcript annotation.<\/p>\n

To improve the accuracy of their next-generation sequencing services further,\u00a0Novogene\u00a0launched a new product named Falcon in March 2020. Falcon is the first intelligent multi-product delivery platform for high-throughput NGS. Falcon promises to offer faster delivery with a more stable quality by eliminating human error and\u00a0increasing efficiency. This platform will provide\u00a0Novogene\u2019s customers with an intelligent and robust service that can process up to\u00a02850\u00a0samples each day. This new platform aims to increase the quality of Novogene\u2019s services and\u00a0meet\u00a0the sequencing requirements of its customers.<\/p>\n

The founder and CEO of Novogene, Dr Li Ruiqiang said, \u201cLeveraging our years of expertise in genomic sequencing has enabled Novogene to develop and launch the first intelligent multi-product NGS delivery platform, which will provide a cutting-edge sequencing solution for customers. As a safe and accurate one-stop ground-breaking solution, Falcon enables faster delivery with more stable quality. As a leading provider of genomic services and solutions in the world, we want to be better positioned to drive innovation in the industry, to lead the industry in the direction towards becoming digital and automated, to propel the establishment of industry standards, and to eventually achieve intelligent transformation.\u201d<\/p>\n

To get more information about Novogene services, please visit our website: novogene.com\/us-en
\n<\/i>
\nOr contact us here. Your dedicated Novogene representative will reach out to you within ONE business day.<\/i> <\/i><\/p>\n<\/div>\n","protected":false},"featured_media":15407,"parent":0,"template":"","yoast_head":"\nHigh Throughput RNA-seq unveils Transcriptome Mystery at Novogene - Novogene<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.novogene.com\/us-en\/resources\/blog\/high-throughput-rna-seq-unveil-transcriptome-mystery-at-novogene\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"High Throughput RNA-seq unveils Transcriptome Mystery at Novogene\" \/>\n<meta property=\"og:description\" content=\"Transcriptome\u00a0analysis examines the complete set of RNA transcripts in a cell using high-throughput RNA-sequencing (RNA-seq). 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