{"id":37273,"date":"2024-09-27T00:34:31","date_gmt":"2024-09-27T07:34:31","guid":{"rendered":"https:\/\/www.novogene.com\/us-en\/?page_id=37273"},"modified":"2025-03-31T00:35:12","modified_gmt":"2025-03-31T07:35:12","slug":"enzymatic-methyl-sequencing-em-seq","status":"publish","type":"page","link":"https:\/\/www.novogene.com\/us-en\/services\/research-services\/epigenome-sequencing\/enzymatic-methyl-sequencing-em-seq\/","title":{"rendered":"Enzymatic Methyl Sequencing"},"content":{"rendered":"
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\nService Specifications<\/a><\/div>\n<\/div>\n<\/div>\n

DNA methylation<\/strong> at the C5 position of cytosine plays a crucial role in gene expression and chromatin remodelling. As one of the most important research areas in epigenetics, methyl-seq<\/strong> tech is .With the development of high-throughput sequencing technology, WGBS has gradually become the gold standard for DNA methylation sequencing.<\/p>\n

Enzymatic Methyl Sequencing<\/strong> has been developed to overcome the shortcomings of WGBS, an enzyme-based method for the detection of 5mC and 5hmC at the single base level. The enzymatic conversion method is gentler and causes less DNA damage, thereby avoiding DNA molecule cleavage and loss.<\/p>\n","protected":false},"excerpt":{"rendered":"

Service Specifications DNA methylation at the C5 position of cytosine plays a crucial role in gene expression and chromatin remodelling. As one of the most important research areas in epigenetics, methyl-seq tech is .With the development of high-throughput sequencing technology, WGBS has gradually become the gold standard for DNA methylation sequencing. Enzymatic Methyl Sequencing has<\/p>\n","protected":false},"author":14,"featured_media":0,"parent":2155,"menu_order":21,"comment_status":"closed","ping_status":"closed","template":"templates\/page-technical3.php","meta":[],"yoast_head":"\nEnzymatic Methyl Sequencing - Novogene<\/title>\n<meta name=\"description\" content=\"Novogene provides whole genome bisulfite sequencing (WGBS) to efficiently identify methylated cytosines on a genome-wide scale with a single nucleotide resolution.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.novogene.com\/us-en\/services\/research-services\/epigenome-sequencing\/enzymatic-methyl-sequencing-em-seq\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Enzymatic Methyl Sequencing\" \/>\n<meta property=\"og:description\" content=\"Novogene provides whole genome bisulfite sequencing (WGBS) to efficiently identify methylated cytosines on a genome-wide scale with a single nucleotide resolution.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.novogene.com\/us-en\/services\/research-services\/epigenome-sequencing\/enzymatic-methyl-sequencing-em-seq\/\" \/>\n<meta property=\"og:site_name\" content=\"Novogene\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/NovogeneAmerica\/\" \/>\n<meta property=\"article:modified_time\" content=\"2025-03-31T07:35:12+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.novogene.com\/us-en\/wp-content\/uploads\/sites\/4\/2020\/07\/istockphoto-513110674-540x360-2.jpg\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:site\" content=\"@Novogene_Global\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.novogene.com\/us-en\/services\/research-services\/epigenome-sequencing\/enzymatic-methyl-sequencing-em-seq\/\",\"url\":\"https:\/\/www.novogene.com\/us-en\/services\/research-services\/epigenome-sequencing\/enzymatic-methyl-sequencing-em-seq\/\",\"name\":\"Enzymatic Methyl Sequencing - 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