{"id":24497,"date":"2021-09-17T23:14:25","date_gmt":"2021-09-18T06:14:25","guid":{"rendered":"https:\/\/www.novogene.com\/us-en\/?page_id=24497"},"modified":"2025-07-01T20:24:04","modified_gmt":"2025-07-02T03:24:04","slug":"reduced-representation-bisulfite-sequencing-rrbs","status":"publish","type":"page","link":"https:\/\/www.novogene.com\/us-en\/services\/research-services\/epigenome-sequencing\/reduced-representation-bisulfite-sequencing-rrbs\/","title":{"rendered":"Reduced Representation Bisulfite Sequencing (RRBS)"},"content":{"rendered":"<div class=\"clear_p\" style=\"float: right;margin: 0 0 20px 50px\">\n<img decoding=\"async\" class=\"clear_img\" style=\"width: 286px;min-height: 180px\" src=\"https:\/\/www.novogene.com\/us-en\/wp-content\/uploads\/sites\/4\/2020\/04\/istockphoto-493477826-540x360-2.jpg\" alt=\"\" \/><\/p>\n<div class=\"col-sm-12 m-auto text-center\" style=\"padding-top: 20px;padding-left: 0\">\n<span style=\"float: left;background: #3f6992;height: 2.6875rem;width: 2.875rem\"><img decoding=\"async\" style=\"margin-top: 0.25rem\" src=\"https:\/\/www.novogene.com\/us-en\/wp-content\/uploads\/sites\/4\/2021\/01\/Novogene-button-icon-20210129.png\" \/><\/span><\/p>\n<div id=\"top_btn\" class=\"blue btn\" style=\"margin-top: 0px;padding: 8px 1.1875rem;float: left;background: #3789C7;border: none;line-height: 1.6875rem\"><a class=\"\" href=\"https:\/\/www.novogene.com\/us-en\/wp-content\/uploads\/sites\/4\/2022\/07\/21-Detailed-Materials-for-RRBS.pdf\">Service Specifications<\/a><\/div>\n<\/div>\n<\/div>\n<p class=\"blue-box\" style=\"width: 70%;background-color: #e2f2ff!important;padding: 20px;font-family: 'Montserrat-Regular', Arial;color: #032e53;font-size: 16px\">Reduced Representation Bisulfite Sequencing (RRBS) detects millions of novel CpG sites based on the improved bisulfite sequencing method, providing coverage to approximately all gene promoters, CpG islands, gene bodies, repetitive DNA sequences, and regulatory elements. It is an NGS-based sequencing platform and combines bisulfite sequencing and restriction enzymes to analyze the genome regions containing high CpG content. This combination allows reduced representation bisulfite sequencing to enhance the efficacy of the sample utilization and provides a perfect platform for clinical applications and pilot research.<\/p>\n<p style=\"line-height: 24px\">By merging the NGS technology, bisulfite sequencing, and restriction enzymes, Novogene provides genome-wide methylation profiles at very affordable costs.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Service Specifications Reduced Representation Bisulfite Sequencing (RRBS) detects millions of novel CpG sites based on the improved bisulfite sequencing method, providing coverage to approximately all gene promoters, CpG islands, gene bodies, repetitive DNA sequences, and regulatory elements. It is an NGS-based sequencing platform and combines bisulfite sequencing and restriction enzymes to analyze the genome regions<\/p>\n","protected":false},"author":41,"featured_media":0,"parent":2155,"menu_order":8,"comment_status":"closed","ping_status":"closed","template":"templates\/page-technical3.php","meta":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v20.8 (Yoast SEO v20.8) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Reduced Representation Bisulfite Sequencing (RRBS) - Novogene<\/title>\n<meta name=\"description\" content=\"RRBS is a methodical and high-throughput approach for investigating the methylation profiles of the entire genome on a single resolution level.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.novogene.com\/us-en\/services\/research-services\/epigenome-sequencing\/reduced-representation-bisulfite-sequencing-rrbs\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Reduced Representation Bisulfite Sequencing (RRBS)\" \/>\n<meta property=\"og:description\" content=\"RRBS is a methodical and high-throughput approach for investigating the methylation profiles of the entire genome on a single resolution level.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.novogene.com\/us-en\/services\/research-services\/epigenome-sequencing\/reduced-representation-bisulfite-sequencing-rrbs\/\" \/>\n<meta property=\"og:site_name\" content=\"Novogene\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/NovogeneAmerica\/\" \/>\n<meta property=\"article:modified_time\" content=\"2025-07-02T03:24:04+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.novogene.com\/us-en\/wp-content\/uploads\/sites\/4\/2020\/04\/istockphoto-493477826-540x360-2.jpg\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:site\" content=\"@Novogene_Global\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.novogene.com\/us-en\/services\/research-services\/epigenome-sequencing\/reduced-representation-bisulfite-sequencing-rrbs\/\",\"url\":\"https:\/\/www.novogene.com\/us-en\/services\/research-services\/epigenome-sequencing\/reduced-representation-bisulfite-sequencing-rrbs\/\",\"name\":\"Reduced Representation Bisulfite Sequencing (RRBS) - 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