{"id":22457,"date":"2021-06-16T00:57:08","date_gmt":"2021-06-16T07:57:08","guid":{"rendered":"https:\/\/www.novogene.com\/us-en\/?page_id=22457"},"modified":"2025-07-01T20:23:11","modified_gmt":"2025-07-02T03:23:11","slug":"whole-genome-bisulfite-sequencing","status":"publish","type":"page","link":"https:\/\/www.novogene.com\/us-en\/services\/research-services\/epigenome-sequencing\/whole-genome-bisulfite-sequencing\/","title":{"rendered":"Whole Genome Bisulfite Sequencing (WGBS)"},"content":{"rendered":"
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\nService Specifications<\/a><\/div>\n<\/div>\n<\/div>\n

DNA methylation<\/strong> at the C5 position of cytosine plays a crucial role in gene expression and chromatin remodeling. Perturbations in methylation patterns are associated with tumorigenesis, neurodegenerative diseases and neurological disorders. Bioinformatic analysis of methylomes is widely used in various research areas, including studies on gene regulation, cell differentiation, embryogenesis, aging, occurrence and development of disease, phenotypic diversity and evolution in plants and animals.<\/p>\n

Novogene provides whole genome bisulfite sequencing (WGBS)<\/strong> to efficiently identify methylated cytosines on a genome-wide scale with a single nucleotide resolution. The deep reach of the methylome is imperative for understanding gene expression and multiple biological processes that are subject to epigenetic regulation.<\/p>\n","protected":false},"excerpt":{"rendered":"

Service Specifications DNA methylation at the C5 position of cytosine plays a crucial role in gene expression and chromatin remodeling. Perturbations in methylation patterns are associated with tumorigenesis, neurodegenerative diseases and neurological disorders. Bioinformatic analysis of methylomes is widely used in various research areas, including studies on gene regulation, cell differentiation, embryogenesis, aging, occurrence and<\/p>\n","protected":false},"author":36,"featured_media":0,"parent":2155,"menu_order":21,"comment_status":"closed","ping_status":"closed","template":"templates\/page-technical3.php","meta":[],"yoast_head":"\nWhole Genome Bisulfite Sequencing (WGBS) - Novogene<\/title>\n<meta name=\"description\" content=\"Novogene provides whole genome bisulfite sequencing (WGBS) to efficiently identify methylated cytosines on a genome-wide scale with a single nucleotide resolution.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.novogene.com\/us-en\/services\/research-services\/epigenome-sequencing\/whole-genome-bisulfite-sequencing\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Whole Genome Bisulfite Sequencing (WGBS)\" \/>\n<meta property=\"og:description\" content=\"Novogene provides whole genome bisulfite sequencing (WGBS) to efficiently identify methylated cytosines on a genome-wide scale with a single nucleotide resolution.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.novogene.com\/us-en\/services\/research-services\/epigenome-sequencing\/whole-genome-bisulfite-sequencing\/\" \/>\n<meta property=\"og:site_name\" content=\"Novogene\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/NovogeneAmerica\/\" \/>\n<meta property=\"article:modified_time\" content=\"2025-07-02T03:23:11+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.novogene.com\/us-en\/wp-content\/uploads\/sites\/4\/2020\/07\/istockphoto-513110674-540x360-2.jpg\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:site\" content=\"@Novogene_Global\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.novogene.com\/us-en\/services\/research-services\/epigenome-sequencing\/whole-genome-bisulfite-sequencing\/\",\"url\":\"https:\/\/www.novogene.com\/us-en\/services\/research-services\/epigenome-sequencing\/whole-genome-bisulfite-sequencing\/\",\"name\":\"Whole Genome Bisulfite Sequencing (WGBS) - 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