{"id":20181,"date":"2021-05-17T00:21:41","date_gmt":"2021-05-17T07:21:41","guid":{"rendered":"https:\/\/www.novogene.com\/us-en\/?page_id=20181"},"modified":"2025-04-09T14:46:06","modified_gmt":"2025-04-09T21:46:06","slug":"human-whole-exome-sequencing","status":"publish","type":"page","link":"https:\/\/www.novogene.com\/us-en\/services\/research-services\/genome-sequencing\/target-capture-sequencing\/human-whole-exome-sequencing\/","title":{"rendered":"Human Whole Exome Sequencing"},"content":{"rendered":"<div class=\"clear_p\" style=\"float: right;margin: 0 0 20px 50px\"><img decoding=\"async\" class=\"clear_img\" style=\"width: 286px;min-height: 280px\" src=\"https:\/\/www.novogene.com\/us-en\/wp-content\/uploads\/sites\/4\/2021\/05\/istockphoto-1140489499-540x360-3-300x200-1.jpg\" alt=\"\" \/><\/p>\n<div class=\"col-sm-12 m-auto text-center\" style=\"padding-top: 20px;padding-left: 0\"><span style=\"float: left;background: #3f6992;height: 2.6875rem;width: 2.875rem\"><img decoding=\"async\" style=\"margin-top: 0.25rem\" src=\"https:\/\/www.novogene.com\/us-en\/wp-content\/uploads\/sites\/4\/2021\/01\/Novogene-button-icon-20210129.png\" \/><\/span><\/p>\n<div id=\"top_btn\" class=\"blue btn\" style=\"margin-top: 0px;padding: 8px 1.1875rem;float: left;background: #3789C7;border: none;line-height: 1.6875rem\"><a class=\"\" href=\"https:\/\/www.novogene.com\/us-en\/wp-content\/uploads\/sites\/4\/2024\/02\/5-Detailed-Materials-for-hWES.pdf\">Service Specifications<\/a><\/div>\n<\/div>\n<\/div>\n<p class=\"blue-box\" style=\"background-color: #e2f2ff!important;padding: 20px;font-family: 'Montserrat-Regular', Arial;color: #032e53;font-size: 16px\"><strong>Whole exome sequencing (WES)<\/strong> employs <strong>next-generation<\/strong> <strong>sequencing technology (NGS)<\/strong>, which provides a cost-efficient alternative to <a href=\"https:\/\/www.novogene.com\/us-en\/services\/research-services\/genome-sequencing\/whole-genome-sequencing\" target=\"_blank\" rel=\"noopener noreferrer\"><strong>whole genome sequencing (WGS)<\/strong><\/a>. The human whole exome, composed by about 180,000 exons (protein-coding region of the genome) accounts for only 1-2% of the human genome, but up to 85% of the disease-related mutations associated with Mendelian disorders occur in these regions <a href=\"https:\/\/www.nature.com\/articles\/jhg2013114\" target=\"_blank\" rel=\"noopener noreferrer\"><sup>[1]<\/sup><\/a>. By targeting these regions, <strong>human whole exome sequencing (hWES)<\/strong> provides an in-depth sequencing and analysis approach to indicate genome variants, germline mutations, somatic mutations, and pathogenic mechanisms. <strong>hWES<\/strong> service supports a broad range of studies for researchers, including genetic disease-related variants, complex diseases, cancer research, or human population genetics.<\/p>\n<p style=\"line-height: 24px\">Novogene\u2019s <strong>hWES service<\/strong> offers a convenient solution with plenty of profits, such as high-quality data, publication-ready results that help you achieve your research goals. Novogene is equipped with clinical-grade sequencing laboratories that are validated and comply with <a href=\"https:\/\/www.novogene.com\/us-en\/technology\/certification\" target=\"_blank\" rel=\"noopener noreferrer\"><strong>CLIA\/CAP\/ISO17025<\/strong><\/a> standards, providing precise diagnosis with our <a href=\"https:\/\/www.novogene.com\/us-en\/clinical-diagnostics\/clinical-whole-exome-sequencing\/clinical-whole-exome-sequencing-clia-cap\/\" target=\"_blank\" rel=\"noopener noreferrer\"><strong>clinical whole exome sequencing<\/strong><\/a> service.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Service Specifications Whole exome sequencing (WES) employs next-generation sequencing technology (NGS), which provides a cost-efficient alternative to whole genome sequencing (WGS). The human whole exome, composed by about 180,000 exons (protein-coding region of the genome) accounts for only 1-2% of the human genome, but up to 85% of the disease-related mutations associated with Mendelian disorders<\/p>\n","protected":false},"author":10,"featured_media":0,"parent":1465,"menu_order":152,"comment_status":"closed","ping_status":"closed","template":"templates\/page-technical2.php","meta":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v20.8 (Yoast SEO v20.8) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Human Whole Exome Sequencing - Novogene<\/title>\n<meta name=\"description\" content=\"Human whole exome sequencing (hWES) targets the protein-coding region of the human genome and provides a cost-effective alternative to whole genome sequencing.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.novogene.com\/us-en\/services\/research-services\/genome-sequencing\/target-capture-sequencing\/human-whole-exome-sequencing\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Human Whole Exome Sequencing\" \/>\n<meta property=\"og:description\" content=\"Human whole exome sequencing (hWES) targets the protein-coding region of the human genome and provides a cost-effective alternative to whole genome sequencing.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.novogene.com\/us-en\/services\/research-services\/genome-sequencing\/target-capture-sequencing\/human-whole-exome-sequencing\/\" \/>\n<meta property=\"og:site_name\" content=\"Novogene\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/NovogeneAmerica\/\" \/>\n<meta property=\"article:modified_time\" content=\"2025-04-09T21:46:06+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.novogene.com\/us-en\/wp-content\/uploads\/sites\/4\/2021\/05\/istockphoto-1140489499-540x360-3-300x200-1.jpg\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:site\" content=\"@Novogene_Global\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.novogene.com\/us-en\/services\/research-services\/genome-sequencing\/target-capture-sequencing\/human-whole-exome-sequencing\/\",\"url\":\"https:\/\/www.novogene.com\/us-en\/services\/research-services\/genome-sequencing\/target-capture-sequencing\/human-whole-exome-sequencing\/\",\"name\":\"Human Whole Exome Sequencing - 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