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Epigenome Sequencing

Novogene provides bisulfite sequencing including Whole Genome Bisulfite Sequencing (WGBS) Enzymatic Methyl Sequencing (EM-Seq) and Reduced-Representation Bisulfite Sequencing (RRBS) for the detection of methylated cytosines on a genome-wide scale with a single nucleotide resolution. This provides insight into the modifying effects of methylation on gene function and expression. With our ChIP-seq and RIP-seq services, protein-DNA interactions (ChIP-seq) and RNA-protein interactions (RIP-seq) can be effectively analyzed.

Technology

Sequencing Platform

  • ILLUMINA

    NovaSeq 6000

    System specifications:

    80Gb - 6Tb output range, 1.6 - 40 B paired end reads per run, and PE150, PE250, PE50, etc.c

  • ILLUMINA

    NovaSeq X Plus

    System specifications:

    65Gb - 16Tb output range, 3.2 - 52 B paired end reads per run, and PE50, PE100, PE150, etc.c