{"id":38579,"date":"2026-01-19T19:52:54","date_gmt":"2026-01-20T03:52:54","guid":{"rendered":"https:\/\/www.novogene.com\/eu-en\/?page_id=38579"},"modified":"2026-02-04T13:48:15","modified_gmt":"2026-02-04T21:48:15","slug":"5-gex-scrna-seq-for-gene-expression-and-immune-profiling","status":"publish","type":"page","link":"https:\/\/www.novogene.com\/eu-en\/services\/research-services\/single-cell-rna-sequencing\/5-gex-scrna-seq-for-gene-expression-and-immune-profiling\/","title":{"rendered":"5&#8242; GEX (scRNA-seq\u00a0for gene expression and immune profiling)"},"content":{"rendered":"<div class=\"clear_p\" style=\"float: right;margin: 0 0 20px 50px;\">\n<img decoding=\"async\" class=\"clear_img\" style=\"width: 286px;min-height: 180px\" src=\"https:\/\/www.novogene.com\/eu-en\/wp-content\/uploads\/sites\/7\/2026\/01\/2-1.jpg\" alt=\"\" \/><\/p>\n<div class=\"col-sm-12 m-auto text-center\" style=\"padding-top: 10px;padding-left: 0\">\n<span style=\"float: left;background: #3f6992;height: 2.6875rem;width: 2.875rem\"><img decoding=\"async\" style=\"margin-top: 0.25rem\" src=\"https:\/\/www.novogene.com\/eu-en\/wp-content\/uploads\/sites\/7\/2021\/01\/Novogene-button-icon-20210129.png\" \/><\/span><\/p>\n<div id=\"top_btn\" class=\"blue btn\" style=\"margin-top: 0px;padding: 8px 1.1875rem;float: left;background: #3789C7;border: none;line-height: 1.6875rem;width:241px;\"><a class=\"\" href=\"https:\/\/www.novogene.com\/eu-en\/wp-content\/uploads\/sites\/7\/2025\/04\/scRNA-seq-Service-Flyer-2026.pdf\">Sample Requirements<\/a><\/div>\n<\/div>\n<\/div>\n<p class=\"blue-box\" style=\"width: 70%;background-color: #e2f2ff!important;padding: 20px;font-family: 'Montserrat-Regular', Arial;color: #032e53;font-size: 16px\">5\u2032 Gene Expression (GEX) sequencing enables transcriptome profiling at single-cell resolution while preserving information from the 5\u2032 end of transcripts. This approach not only supports robust gene expression analysis across individual cells, but also allows direct integration with immune repertoire profiling, making it particularly valuable for immunology-focused studies.\u00a0<\/p>\n<p style=\"line-height: 24px\" class=\"p-novo\">5\u2032 GEX captures transcriptional heterogeneity among intact immune and non-immune cells,\u00a0facilitating\u00a0the identification of cell types, activation states, and functional programs. When\u00a0combined with T cell receptor (TCR) and B cell receptor (BCR) sequencing, this platform enables simultaneous analysis of gene expression and immune clonality, providing insights into clonal expansion\u00a0and\u00a0immune cell phenotypes.\u00a0<\/p>\n<p style=\"line-height: 24px\" class=\"p-novo\">Overall, 5\u2032 GEX with immune profiling offers a\u00a0platform\u00a0for linking transcriptional states with adaptive immune receptor information, supporting studies of immune development, disease mechanisms, immuno-oncology, autoimmunity, and therapeutic response.\u00a0\u00a0<\/p>\n<p style=\"line-height: 24px\" class=\"p-novo\">At Novogene, our 5\u2032 GEX and immune profiling solutions are powered by the latest 10x Genomics Chromium\u00a0iX\u00a0platform and GEM-X chemistry\u00a0based Universal 5\u2019 Gene Expression assay, delivering high sensitivity, reproducibility, and reliable performance. Our streamlined, end-to-end workflow includes sample processing and quality control, single-cell library preparation, high-throughput sequencing on the NovaSeq X Plus, and comprehensive bioinformatics analysis. We also provide clear, publication-ready visualizations to support intuitive data interpretation and accelerate biological discovery.\u00a0<\/p>\n<style>\n.p-novo strong{font-family: 'Merriweather-Bold', Arial;}\n.ul-novo li{text-align: left;}\n<\/style>\n","protected":false},"excerpt":{"rendered":"<p>Sample Requirements 5\u2032 Gene Expression (GEX) sequencing enables transcriptome profiling at single-cell resolution while preserving information from the 5\u2032 end of transcripts. This approach not only supports robust gene expression analysis across individual cells, but also allows direct integration with immune repertoire profiling, making it particularly valuable for immunology-focused studies.\u00a0 5\u2032 GEX captures transcriptional heterogeneity<\/p>\n","protected":false},"author":14,"featured_media":0,"parent":38558,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"templates\/page-technical3.php","meta":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v20.8 (Yoast SEO v20.8) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>5&#039; GEX (scRNA-seq\u00a0for gene expression and immune profiling) - Novogene<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.novogene.com\/eu-en\/services\/research-services\/single-cell-rna-sequencing\/5-gex-scrna-seq-for-gene-expression-and-immune-profiling\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"5&#039; 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